6X4J
PANK3 complex structure with compound PZ-2863
Summary for 6X4J
| Entry DOI | 10.2210/pdb6x4j/pdb |
| Descriptor | Pantothenate kinase 3, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (6 entities in total) |
| Functional Keywords | pank, substrate, complex, transferase, pantothenate kinase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 43066.76 |
| Authors | White, S.W.,Yun, M. (deposition date: 2020-05-22, release date: 2021-11-24, Last modification date: 2023-10-18) |
| Primary citation | Sharma, L.K.,Yun, M.K.,Subramanian, C.,Tangallapally, R.,Jackowski, S.,Rock, C.O.,White, S.W.,Lee, R.E. LipE guided discovery of isopropylphenyl pyridazines as pantothenate kinase modulators. Bioorg.Med.Chem., 52:116504-116504, 2021 Cited by PubMed: 34814071DOI: 10.1016/j.bmc.2021.116504 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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