7UEX

PANK3 complex structure with compound PZ-4127

Summary for 7UEX

• Entry DOI: 10.2210/pdb7uex/pdb
• Descriptor: Pantothenate kinase 3, ACETATE ION, 2-(4-{2-[4-(6-chloropyridazin-3-yl)piperazin-1-yl]-2-oxoethyl}anilino)-2-oxoethyl acetate, ... (8 entities in total)
• Functional Keywords: pank, transferase, inhibitor, activator, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 43306.76

Authors

White, S.W.,Yun, M.,Lee, R.E. (deposition date: 2022-03-22, release date: 2023-03-29, Last modification date: 2023-10-25)

• Primary citation: Tangallapally, R.,Edwards, A.,Subramanian, C.,Sharma, L.K.,Yun, M.,White, S.W.,Jackowski, S.,Rock, C.O.,Lee, R.E.; Discovery of hPANK Activators with Improved Pharmacological Properties; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)