7UEX
PANK3 complex structure with compound PZ-4127
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Pantothenate kinase 3 | polymer | 380 | 42125.8 | 1 | UniProt (Q9H999) Pfam (PF03630) In PDB | Homo sapiens (human) | hPanK3,Pantothenic acid kinase 3 |
2 | A | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
3 | A | 2-(4-{2-[4-(6-chloropyridazin-3-yl)piperazin-1-yl]-2-oxoethyl}anilino)-2-oxoethyl acetate | non-polymer | 431.9 | 1 | Chemie (MZI) | |||
4 | A | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
5 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
6 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
7 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
8 | water | water | 18.0 | 110 | Chemie (HOH) |
Sequence modifications
A: 12 - 370 (UniProt: Q9H999)
PDB | External Database | Details |
---|---|---|
Met -7 | - | expression tag |
Gly -6 | - | expression tag |
Ser -5 | - | expression tag |
Ser -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
His 1 | - | expression tag |
His 2 | - | expression tag |
Ser 3 | - | expression tag |
Ser 4 | - | expression tag |
Gly 5 | - | expression tag |
Leu 6 | - | expression tag |
Val 7 | - | expression tag |
Pro 8 | - | expression tag |
Arg 9 | - | expression tag |
Gly 10 | - | expression tag |
Ser 11 | - | expression tag |
Asp 371 | - | expression tag |
Asp 372 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 42125.8 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 1181.0 | |
All* | Total formula weight | 43306.8 |