6DBC

Second bromodomain of Human BRD2 with a Tetrahydroquinoline analogue

Summary for 6DBC

• Entry DOI: 10.2210/pdb6dbc/pdb
• Descriptor: Bromodomain-containing protein 2, 1,2-ETHANEDIOL, 1-[(2S,4R)-4-[(2-chlorophenyl)amino]-2-methyl-6-(1H-pyrazol-3-yl)-3,4-dihydroquinolin-1(2H)-yl]ethan-1-one, ... (4 entities in total)
• Functional Keywords: bet, brd2, bromodomain, inhibitor, complex, transcription, transcription-inhibitor complex, transcription/inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 14339.82

Authors

White, S.W.,Yun, M. (deposition date: 2018-05-03, release date: 2019-11-13, Last modification date: 2023-10-04)

• Primary citation: White, S.W.,Yun, M.; Second bromodomain of Human BRD2 with a Tetrahydroquinoline analogue; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.05 Å)