Author results

4ETQ
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VACCINIA VIRUS D8L IMV ENVELOPE PROTEIN IN COMPLEX WITH FAB OF MURINE IGG2A LA5
Descriptor:anti-vaccinia D8L antigen murine monoclonal IgG2a antibody LA5, heavy chain, light chain, ...
Authors:Matho, M.H., Zajonc, D.M.
Deposit date:2012-04-24
Release date:2012-06-06
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Biochemical Characterization of the Vaccinia Virus Envelope Protein D8 and Its Recognition by the Antibody LA5.
J.Virol., 86, 2012
4LQF
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STRUCTURE OF MURINE IGG2B A2C7-FAB IN COMPLEX WITH VACCINIA ANTIGEN A33R AT THE RESOLUTION OF 2.3 ANGSTROMS
Descriptor:A33R, Murine IgG2b A2C7 Heavy chain Fab domain, Murine IgG2b A2C7 Light chain Fab domain, ...
Authors:Matho, M.H., Schlossman, A.M., Zajonc, D.M.
Deposit date:2013-07-17
Release date:2014-08-06
Last modified:2015-09-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Functional Characterization of Anti-A33 Antibodies Reveal a Potent Cross-Species Orthopoxviruses Neutralizer.
Plos Pathog., 11, 2015
4LU5
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STRUCTURE OF MURINE IGG2A A20G2-FAB IN COMPLEX WITH VACCINIA ANTIGEN A33R AT THE RESOLUTION OF 2.9 ANGSTROMS
Descriptor:A33R, Murine IgG2a A20G2 Heavy chain Fab domain, Murine IgG2a A20G2 Light chain Fab domain
Authors:Matho, M.H., Schlossman, A.M., Zajonc, D.M.
Deposit date:2013-07-24
Release date:2014-07-30
Last modified:2015-09-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and Functional Characterization of Anti-A33 Antibodies Reveal a Potent Cross-Species Orthopoxviruses Neutralizer.
Plos Pathog., 11, 2015
4M1G
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STRUCTURE OF MURINE IGG2A A27D7-FAB IN COMPLEX WITH VACCINIA ANTIGEN A33R AT THE RESOLUTION OF 1.6 ANGSTROMS
Descriptor:Murine IgG2a A27D7 Light chain Fab domain, Murine IgG2a A27D7 Heavy chain Fab domain, A33R, ...
Authors:Matho, M.H., Schlossman, A.M., Zajonc, D.M.
Deposit date:2013-08-02
Release date:2014-08-06
Last modified:2015-09-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and Functional Characterization of Anti-A33 Antibodies Reveal a Potent Cross-Species Orthopoxviruses Neutralizer.
Plos Pathog., 11, 2015
4U6H
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VACCINIA L1/M12B9-FAB COMPLEX
Descriptor:Heavy chain of murine anti-vaccinia L1 IgG2a antibody M12B9, Light chain of murine anti-vaccinia L1 IgG2a antibody M12B9, Protein L1
Authors:Matho, M.H., Schlossman, A., Zajonc, D.M.
Deposit date:2014-07-29
Release date:2014-08-06
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Potent neutralization of vaccinia virus by divergent murine antibodies targeting a common site of vulnerability in l1 protein.
J.Virol., 88, 2014
4ZO5
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PDE10 COMPLEXED WITH 4-ISOPROPOXY-2-(2-(3-(4-METHOXYPHENYL)-4-OXO-3,4-DIHYDROQUINAZOLIN-2-YL)ETHYL)ISOINDOLINE-1,3-DIONE
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, ZINC ION, MAGNESIUM ION, ...
Authors:Yan, Y.
Deposit date:2015-05-06
Release date:2015-08-12
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Discovery of [(11)C]MK-8193 as a PET tracer to measure target engagement of phosphodiesterase 10A (PDE10A) inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
5EOQ
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STRUCTURE OF THE MURINE FAB 1G6 BOUND TO THE VACCINIA VIRUS A27 PEPTIDE 31-40
Descriptor:Anti vaccinia virus A27 antibody Fab 1G6 heavy chain, Anti vaccinia virus A27 antibody Fab 1G6 light chain, Protein A27
Authors:Matho, M.H., Zajonc, D.M.
Deposit date:2015-11-10
Release date:2016-03-02
Last modified:2016-04-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Linear Epitopes in Vaccinia Virus A27 Are Targets of Protective Antibodies Induced by Vaccination against Smallpox.
J.Virol., 90, 2016
5EOR
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STRUCTURE OF THE MURINE ANTIBODY FAB 8E3 BOUND TO THE VACCINIA VIRUS A27 PEPTIDE 101-110
Descriptor:anti vaccinia virus A27 antibody 8E3 heavy chain, anti vaccinia virus A27 antibody 8E3 light chain, Protein A27, ...
Authors:Matho, M.H., Zajonc, D.M.
Deposit date:2015-11-10
Release date:2016-03-02
Last modified:2016-04-27
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Linear Epitopes in Vaccinia Virus A27 Are Targets of Protective Antibodies Induced by Vaccination against Smallpox.
J.Virol., 90, 2016
5USH
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STRUCTURE OF VACCINIA VIRUS D8 PROTEIN BOUND TO HUMAN FAB VV66
Descriptor:IMV membrane protein, Fab vv66 heavy chain, Fab vv66 light chain
Authors:Zajonc, D.M.
Deposit date:2017-02-13
Release date:2017-09-20
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D8.
J. Biol. Chem., 293, 2018
5USL
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STRUCTURE OF VACCINIA VIRUS D8 PROTEIN BOUND TO HUMAN FAB VV304
Descriptor:IMV membrane protein, Fab vv304 Heavy chain, Fab vv304 Light chain
Authors:Zajonc, D.M.
Deposit date:2017-02-13
Release date:2017-09-20
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure-function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D8.
J. Biol. Chem., 293, 2018
6ATF
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HLA-DRB1*1402 IN COMPLEX WITH VIMENTIN59-71
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, MHC class II antigen, ...
Authors:Scally, S.W., Ting, Y.T., Rossjohn, J.
Deposit date:2017-08-29
Release date:2017-09-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis.
Ann. Rheum. Dis., 76, 2017
6ATI
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HLA-DRB1*1402 IN COMPLEX WITH VIMENTIN-64CIT59-71
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, MHC class II antigen, ...
Authors:Scally, S.W., Ting, Y.T., Rossjohn, J.
Deposit date:2017-08-29
Release date:2017-09-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis.
Ann. Rheum. Dis., 76, 2017
6ATZ
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HLA-DRB1*1402 IN COMPLEX WITH CITRULLINATED FIBRINOGEN PEPTIDE
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, MHC class II antigen, ...
Authors:Ting, Y.T., Scally, S.W., Rossjohn, J.
Deposit date:2017-08-29
Release date:2017-09-20
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis.
Ann. Rheum. Dis., 76, 2017
6B9J
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STRUCTURE OF VACCINIA VIRUS D8 PROTEIN BOUND TO HUMAN FAB VV138
Descriptor:IMV membrane protein, Fab vv138 Heavy chain, Fab vv138 Light chain, ...
Authors:Zajonc, D.M.
Deposit date:2017-10-10
Release date:2017-11-22
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure-function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D8.
J. Biol. Chem., 293, 2018
6BR8
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STRUCTURE OF A6 REVEALS A NOVEL LIPID TRANSPORTER
Descriptor:Protein A6 homolog, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate, (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE
Authors:Deng, J., Peng, S., Pathak, P.
Deposit date:2017-11-30
Release date:2018-06-20
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of a lipid-bound viral membrane assembly protein reveals a modality for enclosing the lipid bilayer.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BR9
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STRUCTURE OF A6 REVEALS A NOVEL LIPID TRANSPORTER
Descriptor:Protein A6 homolog, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate, (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE
Authors:Deng, J., Peng, S., Pathak, P.
Deposit date:2017-11-30
Release date:2018-06-20
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a lipid-bound viral membrane assembly protein reveals a modality for enclosing the lipid bilayer.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6CB6
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CRYSTAL STRUCTURE OF VACCINIA VIRUS A6 N-TERMINUS (SPACE GROUP C2)
Descriptor:Protein A6
Authors:Han, Y., Zhang, B., Deng, J.
Deposit date:2018-02-02
Release date:2018-12-12
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of a lipid-bound viral membrane assembly protein reveals a modality for enclosing the lipid bilayer.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6CB7
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CRYSTAL STRUCTURE OF VACCINIA VIRUS A6 N-TERMINUS (SPACE GROUP C2)
Descriptor:Protein A6, NICKEL (II) ION
Authors:Han, Y., Zhang, B., Deng, J.
Deposit date:2018-02-02
Release date:2018-12-12
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of a lipid-bound viral membrane assembly protein reveals a modality for enclosing the lipid bilayer.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DJU
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MTB CLPB IN COMPLEX WITH ATPGAMMAS AND CASEIN, CONFORMER 1
Descriptor:Chaperone protein ClpB, casein polyAlanine model, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Yu, H.J., Li, H.L.
Deposit date:2018-05-26
Release date:2018-09-26
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:ATP hydrolysis-coupled peptide translocation mechanism ofMycobacterium tuberculosisClpB.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DJV
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MTB CLPB IN COMPLEX WITH ATPGAMMAS AND CASEIN, CONFORMER 2
Descriptor:Chaperone protein ClpB, casein polyAlanine model, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Yu, H.J., Li, H.L.
Deposit date:2018-05-26
Release date:2018-09-26
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:ATP hydrolysis-coupled peptide translocation mechanism ofMycobacterium tuberculosisClpB.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6ED3
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MTB CLPB IN COMPLEX WITH AMPPNP
Descriptor:Chaperone protein ClpB
Authors:Yu, H.J., Li, H.L.
Deposit date:2018-08-08
Release date:2018-09-26
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:ATP hydrolysis-coupled peptide translocation mechanism ofMycobacterium tuberculosisClpB.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6NCU
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INTERLEUKIN-37 RESIDUES 53-206- DIMER
Descriptor:Interleukin-37
Authors:Eisenmesser, E.Z.
Deposit date:2018-12-12
Release date:2019-03-13
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Interleukin-37 monomer is the active form for reducing innate immunity.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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