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5FKW
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BU of 5fkw by Molmil
cryo-EM structure of the E. coli replicative DNA polymerase complex bound to DNA (DNA polymerase III alpha, beta, epsilon)
Descriptor: DNA POLYMERASE III ALPHA, DNA POLYMERASE III BETA, DNA POLYMERASE III EPSILON, ...
Authors:Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H.
Deposit date:2015-10-20
Release date:2015-11-25
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:cryo-EM structures of theE. colireplicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease andtau.
Elife, 4, 2015
5FN5
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BU of 5fn5 by Molmil
Cryo-EM structure of gamma secretase in class 3 of the apo- state ensemble
Descriptor: Gamma-secretase subunit APH-1A, Gamma-secretase subunit PEN-2, Nicastrin, ...
Authors:Bai, X.C, Rajendra, E, Yang, G.H, Shi, Y.G, Scheres, S.H.W.
Deposit date:2015-11-10
Release date:2015-12-16
Last modified:2019-09-11
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
5FKV
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BU of 5fkv by Molmil
cryo-EM structure of the E. coli replicative DNA polymerase complex bound to DNA (DNA polymerase III alpha, beta, epsilon, tau complex)
Descriptor: DNA POLYMERASE III BETA, DNA POLYMERASE III EPSILON, DNA POLYMERASE III SUBUNIT ALPHA, ...
Authors:Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H.
Deposit date:2015-10-20
Release date:2015-11-25
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (8.04 Å)
Cite:cryo-EM structures of theE. colireplicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease andtau.
Elife, 4, 2015
5M1S
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BU of 5m1s by Molmil
Cryo-EM structure of the E. coli replicative DNA polymerase-clamp-exonuclase-theta complex bound to DNA in the editing mode
Descriptor: DNA Primer Strand, DNA Template Strand, DNA polymerase III subunit alpha, ...
Authors:Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H.
Deposit date:2016-10-10
Release date:2017-01-18
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Self-correcting mismatches during high-fidelity DNA replication.
Nat. Struct. Mol. Biol., 24, 2017
5GAN
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BU of 5gan by Molmil
The overall structure of the yeast spliceosomal U4/U6.U5 tri-snRNP at 3.7 Angstrom
Descriptor: 13 kDa ribonucleoprotein-associated protein, GUANOSINE-5'-TRIPHOSPHATE, Pre-mRNA-processing factor 31, ...
Authors:Nguyen, T.H.D, Galej, W.P, Bai, X.C, Oubridge, C, Scheres, S.H.W, Newman, A.J, Nagai, K.
Deposit date:2015-12-15
Release date:2016-01-27
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nature, 530, 2016
5GAO
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BU of 5gao by Molmil
Head region of the yeast spliceosomal U4/U6.U5 tri-snRNP
Descriptor: Pre-mRNA-splicing factor 8, Pre-mRNA-splicing helicase BRR2, Saccharomyces cerevisiae strain UOA_M2 chromosome 5 sequence, ...
Authors:Nguyen, T.H.D, Galej, W.P, Bai, X.C, Oubridge, C, Scheres, S.H.W, Newman, A.J, Nagai, K.
Deposit date:2015-12-15
Release date:2016-01-27
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nature, 530, 2016
5MZ6
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BU of 5mz6 by Molmil
Cryo-EM structure of a Separase-Securin complex from Caenorhabditis elegans at 3.8 A resolution
Descriptor: Interactor of FizzY protein, SEParase
Authors:Boland, A, Martin, T.G, Zhang, Z, Yang, J, Bai, X.C, Chang, L, Scheres, S.H.W, Barford, D.
Deposit date:2017-01-31
Release date:2017-03-08
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of a metazoan separase-securin complex at near-atomic resolution.
Nat. Struct. Mol. Biol., 24, 2017
6OKK
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BU of 6okk by Molmil
Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Wong, W, Scheres, S.H.W.
Deposit date:2019-04-13
Release date:2019-05-22
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
Elife, 3, 2014
6QJH
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BU of 6qjh by Molmil
Cryo-EM structure of heparin-induced 2N4R tau snake filaments
Descriptor: Microtubule-associated protein tau
Authors:Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W.
Deposit date:2019-01-24
Release date:2019-02-20
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
6QJM
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BU of 6qjm by Molmil
Cryo-EM structure of heparin-induced 2N4R tau twister filaments
Descriptor: Microtubule-associated protein tau
Authors:Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W.
Deposit date:2019-01-24
Release date:2019-02-27
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
6QJQ
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BU of 6qjq by Molmil
Cryo-EM structure of heparin-induced 2N3R tau filaments
Descriptor: Microtubule-associated protein tau
Authors:Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W.
Deposit date:2019-01-24
Release date:2019-02-20
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
6RZA
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BU of 6rza by Molmil
Cryo-EM structure of the human inner arm dynein DNAH7 microtubule binding domain bound to microtubules
Descriptor: Cytoplasmic dynein 1 heavy chain 1,Dynein heavy chain 7, axonemal,Cytoplasmic dynein 1 heavy chain 1, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Lacey, S.E, He, S, Scheres, S.H.W, Carter, A.P.
Deposit date:2019-06-13
Release date:2019-07-10
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-EM of dynein microtubule-binding domains shows how an axonemal dynein distorts the microtubule.
Elife, 8, 2019
6QJP
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BU of 6qjp by Molmil
Cryo-EM structure of heparin-induced 2N4R tau jagged filaments
Descriptor: Microtubule-associated protein tau
Authors:Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W.
Deposit date:2019-01-24
Release date:2019-02-20
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
6RZB
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BU of 6rzb by Molmil
Cryo-EM structure of mouse cytoplasmic dynein-1 microtubule binding domain bound to microtubules
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Lacey, S.E, He, S, Scheres, S.H.W, Carter, A.P.
Deposit date:2019-06-13
Release date:2019-07-10
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Cryo-EM of dynein microtubule-binding domains shows how an axonemal dynein distorts the microtubule.
Elife, 8, 2019
5FKU
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BU of 5fku by Molmil
cryo-EM structure of the E. coli replicative DNA polymerase complex in DNA free state (DNA polymerase III alpha, beta, epsilon, tau complex)
Descriptor: DNA POLYMERASE III SUBUNIT ALPHA, DNA POLYMERASE III SUBUNIT BETA, DNA POLYMERASE III SUBUNIT EPSILON, ...
Authors:Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H.
Deposit date:2015-10-20
Release date:2015-11-25
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (8.34 Å)
Cite:cryo-EM structures of theE. colireplicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease andtau.
Elife, 4, 2015
5FN3
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BU of 5fn3 by Molmil
Cryo-EM structure of gamma secretase in class 1 of the apo- state ensemble
Descriptor: Gamma-secretase subunit APH-1A, Gamma-secretase subunit PEN-2, Nicastrin, ...
Authors:Bai, X.C, Rajendra, E, Yang, G.H, Shi, Y.G, Scheres, S.H.W.
Deposit date:2015-11-10
Release date:2015-12-16
Last modified:2019-09-11
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
5FN2
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BU of 5fn2 by Molmil
Cryo-EM structure of gamma secretase in complex with a drug DAPT
Descriptor: Gamma-secretase subunit APH-1A, Gamma-secretase subunit PEN-2, Nicastrin, ...
Authors:Bai, X.C, Rajendra, E, Yang, G.H, Shi, Y.G, Scheres, S.H.W.
Deposit date:2015-11-10
Release date:2015-12-16
Last modified:2019-09-04
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
5FN4
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BU of 5fn4 by Molmil
Cryo-EM structure of gamma secretase in class 2 of the apo- state ensemble
Descriptor: Gamma-secretase subunit APH-1A, Gamma-secretase subunit PEN-2, Nicastrin, ...
Authors:Bai, X.C, Rajendra, E, Yang, G.H, Shi, Y.G, Scheres, S.H.W.
Deposit date:2015-11-10
Release date:2015-12-16
Last modified:2019-09-11
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
3J79
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BU of 3j79 by Molmil
Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, large subunit
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Wong, W, Bai, X.C, Brown, A, Fernandez, I.S, Hanssen, E, Condron, M, Tan, Y.H, Baum, J, Scheres, S.H.W.
Deposit date:2014-06-02
Release date:2014-07-16
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
Elife, 3, 2014
3J7P
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BU of 3j7p by Molmil
Structure of the 80S mammalian ribosome bound to eEF2
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S.
Deposit date:2014-08-01
Release date:2014-09-03
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014
3J7R
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BU of 3j7r by Molmil
Structure of the translating mammalian ribosome-Sec61 complex
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S.
Deposit date:2014-08-01
Release date:2014-09-03
Last modified:2019-10-30
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014
3J6B
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BU of 3j6b by Molmil
Structure of the yeast mitochondrial large ribosomal subunit
Descriptor: 21S ribosomal RNA, 54S ribosomal protein IMG1, mitochondrial, ...
Authors:Amunts, A, Brown, A, Bai, X.C, Llacer, J.L, Hussain, T, Emsley, P, Long, F, Murshudov, G, Scheres, S.H.W, Ramakrishnan, V.
Deposit date:2014-01-22
Release date:2014-04-09
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of the yeast mitochondrial large ribosomal subunit.
Science, 343, 2014
3J7O
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BU of 3j7o by Molmil
Structure of the mammalian 60S ribosomal subunit
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S.
Deposit date:2014-08-01
Release date:2014-09-03
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014
3J8H
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BU of 3j8h by Molmil
Structure of the rabbit ryanodine receptor RyR1 in complex with FKBP12 at 3.8 Angstrom resolution
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ZINC ION
Authors:Yan, Z, Bai, X, Yan, C, Wu, J, Scheres, S.H.W, Shi, Y, Yan, N.
Deposit date:2014-10-26
Release date:2014-12-10
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution.
Nature, 517, 2015
3J7A
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BU of 3j7a by Molmil
Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit
Descriptor: 18S ribosomal RNA, 40S ribosomal protein eS1, 40S ribosomal protein eS10, ...
Authors:Wong, W, Bai, X.C, Brown, A, Fernandez, I.S, Hanssen, E, Condron, M, Tan, Y.H, Baum, J, Scheres, S.H.W.
Deposit date:2014-06-03
Release date:2014-07-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
Elife, 3, 2014

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