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6QJM

Cryo-EM structure of heparin-induced 2N4R tau twister filaments

Summary for 6QJM
Entry DOI10.2210/pdb6qjm/pdb
EMDB information4564
DescriptorMicrotubule-associated protein tau (1 entity in total)
Functional Keywordsrecombinant tau protein, heparin, filament, cross-beta structure, protein fibril
Biological sourceHomo sapiens (Human)
Total number of polymer chains3
Total formula weight15567.24
Authors
Zhang, W.,Falcon, B.,Murzin, A.G.,Fan, J.,Crowther, R.A.,Goedert, M.,Scheres, S.H.W. (deposition date: 2019-01-24, release date: 2019-02-27)
Primary citationZhang, W.,Falcon, B.,Murzin, A.G.,Fan, J.,Crowther, R.A.,Goedert, M.,Scheres, S.H.
Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8:-, 2019
Cited by
PubMed: 30720432
DOI: 10.7554/eLife.43584
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.3 Å)
Structure validation

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