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5F74
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Crystal structure of ChREBP:14-3-3 complex bound with AMP
分子名称: 14-3-3 protein beta/alpha, ADENOSINE MONOPHOSPHATE, Carbohydrate-responsive element-binding protein
著者Jung, H, Uyeda, K.
登録日2015-12-07
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Metabolite Regulation of Nuclear Localization of Carbohydrate-response Element-binding Protein (ChREBP): ROLE OF AMP AS AN ALLOSTERIC INHIBITOR.
J.Biol.Chem., 291, 2016
5EYO
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BU of 5eyo by Molmil
The crystal structure of the Max bHLH domain in complex with 5-carboxyl cytosine DNA
分子名称: DNA (5'-D(*AP*GP*TP*AP*GP*CP*AP*(1CC)P*GP*TP*GP*CP*TP*AP*CP*T)-3'), Protein max
著者Wang, D, Hashimoto, H, Zhang, X, Cheng, X.
登録日2015-11-25
公開日2016-12-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献MAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myeloma.
Nucleic Acids Res., 45, 2017
4ZQD
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BU of 4zqd by Molmil
Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex with the Benzoxadiazole Antagonist 0X3
分子名称: Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, N-(3-chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine
著者Wu, D, Potluri, N, Lu, J, Kim, Y, Rastinejad, F.
登録日2015-05-09
公開日2015-08-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献Structural integration in hypoxia-inducible factors.
Nature, 524, 2015
4ZPR
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BU of 4zpr by Molmil
Crystal Structure of the Heterodimeric HIF-1a:ARNT Complex with HRE DNA
分子名称: Aryl hydrocarbon receptor nuclear translocator, DNA (5'-D(*CP*AP*CP*GP*AP*CP*CP*CP*GP*CP*AP*CP*GP*TP*AP*CP*GP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*GP*CP*TP*GP*CP*GP*TP*AP*CP*GP*TP*GP*CP*GP*GP*GP*TP*CP*GP*T)-3'), ...
著者Wu, D, Potluri, N, Lu, J, Kim, Y, Rastinejad, F.
登録日2015-05-08
公開日2015-08-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.902 Å)
主引用文献Structural integration in hypoxia-inducible factors.
Nature, 524, 2015
4ZPK
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Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex with HRE DNA
分子名称: Aryl hydrocarbon receptor nuclear translocator, DNA (5'-D(*CP*AP*CP*GP*AP*CP*CP*CP*GP*CP*AP*CP*GP*TP*AP*CP*GP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*GP*CP*TP*GP*CP*GP*TP*AP*CP*GP*TP*GP*CP*GP*GP*GP*TP*CP*GP*T)-3'), ...
著者Wu, D, Potluri, N, Lu, J, Kim, Y, Rastinejad, F.
登録日2015-05-08
公開日2015-08-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structural integration in hypoxia-inducible factors.
Nature, 524, 2015
4ZP4
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BU of 4zp4 by Molmil
Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex
分子名称: Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1
著者Wu, D, Potluri, N, Lu, J, Kim, Y, Rastinejad, F.
登録日2015-05-07
公開日2015-08-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.355 Å)
主引用文献Structural integration in hypoxia-inducible factors.
Nature, 524, 2015
4ZPH
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Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex with Proflavine
分子名称: Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, PROFLAVIN
著者Wu, D, Potluri, N, Lu, J, Kim, Y, Rastinejad, F.
登録日2015-05-07
公開日2015-08-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural integration in hypoxia-inducible factors.
Nature, 524, 2015
4YZ6
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Crystal Structure of Myc3[44-238] from Arabidopsis in complex with Jaz1 peptide [200-221]
分子名称: Protein TIFY 10A, Transcription factor MYC3
著者Ke, J, Zhang, F, Brunzelle, J, Xu, H.E, Melcher, K, HE, S.Y.
登録日2015-03-24
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
4YWC
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BU of 4ywc by Molmil
Crystal structure of Myc3(5-242) fragment in complex with Jaz9(218-239) peptide
分子名称: Protein TIFY 7, Transcription factor MYC3
著者Ke, J, Zhang, F, Brunzelle, J.S, Xu, H.E, Melcher, K, He, S.Y.
登録日2015-03-20
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
4RS9
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BU of 4rs9 by Molmil
Structure of Myc3 N-terminal JAZ-binding domain [44-238] in complex with Jas motif of JAZ9
分子名称: Protein TIFY 7, Transcription factor MYC3
著者Ke, J, Zhang, F, Zhou, X.E, Brunzelle, J.S, Zhou, M, Xu, H.E, Melcher, K, He, S.Y.
登録日2014-11-07
公開日2015-08-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
4RRU
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BU of 4rru by Molmil
Myc3 N-terminal JAZ-binding domain[5-242] from arabidopsis
分子名称: CALCIUM ION, Transcription factor MYC3
著者Ke, J, Zhang, F, Zhou, X.E, Brunzelle, J.S, Zhou, M, Xu, H.E, Melcher, K, He, S.Y.
登録日2014-11-06
公開日2015-08-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
4RQW
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BU of 4rqw by Molmil
Crystal structure of Myc3 N-terminal JAZ-binding domain [44-238] from Arabidopsis
分子名称: CALCIUM ION, Transcription factor MYC3
著者Ke, J, Zhang, F, Zhou, X.E, Brunzelle, J, Zhou, M, Xu, H.E, Melcher, K, He, S.Y.
登録日2014-11-05
公開日2015-08-12
最終更新日2015-09-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
2MH3
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BU of 2mh3 by Molmil
NMR structure of the basic helix-loop-helix region of the transcriptional repressor HES-1
分子名称: Transcription factor HES-1
著者Wienk, H, Popovic, M, Coglievina, M, Boelens, R, Pongor, S, Pintar, A.
登録日2013-11-15
公開日2014-02-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The basic helix-loop-helix region of the transcriptional repressor hairy and enhancer of split 1 is preorganized to bind DNA.
Proteins, 82, 2014
4M4X
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BU of 4m4x by Molmil
Structure and Dimerization Properties of the Aryl Hydrocarbon Receptor (AHR) PAS-A Domain
分子名称: Aryl hydrocarbon receptor
著者Wu, D, Potluri, N, Kim, Y, Rastinejad, F.
登録日2013-08-07
公開日2013-09-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.551 Å)
主引用文献Structure and dimerization properties of the aryl hydrocarbon receptor PAS-A domain.
Mol.Cell.Biol., 33, 2013
4KFZ
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BU of 4kfz by Molmil
Crystal structure of LMO2 and anti-LMO2 VH complex
分子名称: Anti-LMO2 VH, LMO-2, ZINC ION
著者Sewell, H, Tanaka, T, El Omari, K, Cruz-Migoni, A, Mancini, E.J, Fuentes-Fernandez, N, Chambers, J, Rabbitts, T.H.
登録日2013-04-28
公開日2014-01-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Conformational flexibility of the oncogenic protein LMO2 primes the formation of the multi-protein transcription complex.
Sci Rep, 4, 2014
2YPB
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BU of 2ypb by Molmil
Structure of the SCL:E47 complex bound to DNA
分子名称: EBOX FORWARD, EBOX REVERSE, T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1, ...
著者El Omari, K, Hoosdally, S.J, Tuladhar, K, Karia, D, Ponsele, E, Platonova, O, Vyas, P, Patient, R, Porcher, C, Mancini, E.J.
登録日2012-10-30
公開日2013-07-31
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献Structural Basis for Lmo2-Driven Recruitment of the Scl:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets.
Cell Rep., 4, 2013
2YPA
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BU of 2ypa by Molmil
Structure of the SCL:E47:LMO2:LDB1 complex bound to DNA
分子名称: EBOX FORWARD, EBOX REVERSE, LIM DOMAIN-BINDING PROTEIN 1, ...
著者El Omari, K, Hoosdally, S.J, Tuladhar, K, Karia, D, Ponsele, E, Platonova, O, Vyas, P, Patient, R, Porcher, C, Mancini, E.J.
登録日2012-10-30
公開日2013-07-31
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for Lmo2-Driven Recruitment of the Scl:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets.
Cell Rep., 4, 2013
4H10
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BU of 4h10 by Molmil
Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic Helix-Loop-Helix domains with E-box DNA
分子名称: Aryl hydrocarbon receptor nuclear translocator-like protein 1, Circadian locomoter output cycles protein kaput, E-box DNA antisense strand, ...
著者Wang, Z, Su, X.-D.
登録日2012-09-10
公開日2012-12-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic helix-loop-helix domains with E-box DNA.
Cell Res., 23, 2013
4F3L
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BU of 4f3l by Molmil
Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex
分子名称: BMAL1b, Circadian locomoter output cycles protein kaput
著者Huang, N, Chelliah, Y, Shan, Y, Taylor, C, Yoo, S, Partch, C, Green, C.B, Zhang, H, Takahashi, J.
登録日2012-05-09
公開日2012-06-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.268 Å)
主引用文献Crystal structure of the heterodimeric CLOCK:BMAL1 transcriptional activator complex.
Science, 337, 2012
3U5V
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BU of 3u5v by Molmil
Crystal structure of Max-E47
分子名称: NITRATE ION, Protein max, Transcription factor E2-alpha chimera
著者Guarne, A, Ahmadpour, F, Gloyd, M.
登録日2011-10-11
公開日2012-03-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the minimalist max-e47 protein chimera.
Plos One, 7, 2012
3AY5
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BU of 3ay5 by Molmil
Crystal structure of HHM (human homologue of murine maternal Id-like molecule)
分子名称: Cyclin-D1-binding protein 1
著者Seto, A, Ishitani, R, Nureki, O.
登録日2011-04-28
公開日2012-03-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of a dominant-negative helix-loop-helix transcriptional regulator suggests mechanisms of autoinhibition.
Embo J., 31, 2012
3PXP
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BU of 3pxp by Molmil
Crystal structure of a PAS and DNA binding domain containing protein (Caur_2278) from CHLOROFLEXUS AURANTIACUS J-10-FL at 2.30 A resolution
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Helix-turn-helix domain protein, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2010-12-10
公開日2011-01-19
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of an MmyB-Like Regulator from C. aurantiacus, Member of a New Transcription Factor Family Linked to Antibiotic Metabolism in Actinomycetes.
Plos One, 7, 2012
3F1P
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Crystal structure of a high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains
分子名称: Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1
著者Scheuermann, T.H, Tomchick, D.R, Machius, M, Guo, Y, Bruick, R.K, Gardner, K.H.
登録日2008-10-28
公開日2009-01-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.17 Å)
主引用文献Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.
Proc.Natl.Acad.Sci.USA, 106, 2009
3F1O
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BU of 3f1o by Molmil
Crystal structure of the high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains, with an internally-bound artificial ligand
分子名称: 1,2-ETHANEDIOL, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, ...
著者Scheuermann, T.H, Tomchick, D.R, Machius, M, Guo, Y, Bruick, R.K, Gardner, K.H.
登録日2008-10-28
公開日2009-01-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.598 Å)
主引用文献Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.
Proc.Natl.Acad.Sci.USA, 106, 2009
3F1N
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Crystal structure of a high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains, with internally bound ethylene glycol.
分子名称: 1,2-ETHANEDIOL, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1
著者Scheuermann, T.H, Tomchick, D.R, Machius, M, Guo, Y, Bruick, R.K, Gardner, K.H.
登録日2008-10-28
公開日2009-01-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.479 Å)
主引用文献Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.
Proc.Natl.Acad.Sci.USA, 106, 2009

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