2YPB

Structure of the SCL:E47 complex bound to DNA

Summary for 2YPB

Related1HLH 2YPA
DescriptorT-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1, TRANSCRIPTION FACTOR E2-ALPHA, EBOX FORWARD, ... (4 entities in total)
Functional Keywordsimmune system, hematopoiesis, leukemia
Biological sourceHOMO SAPIENS (HUMAN)
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Cellular locationNucleus (By similarity) P17542
Nucleus P15923
Total number of polymer chains4
Total molecular weight27101.75
Authors
Primary citation
El Omari, K.,Hoosdally, S.J.,Tuladhar, K.,Karia, D.,Hall-Ponsele, E.,Platonova, O.,Vyas, P.,Patient, R.,Porcher, C.,Mancini, E.J.
Structural Basis for Lmo2-Driven Recruitment of the Scl:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets.
Cell Rep., 4:135-, 2013
PubMed: 23831025 (PDB entries with the same primary citation)
DOI: 10.1016/J.CELREP.2013.06.008
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.87 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.28650 0.8% 3.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171916
PDB entries from 2020-12-02