2YPB

Structure of the SCL:E47 complex bound to DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1	polymer	91	10721.1	1	UniProt (P17542) Pfam (PF00010) In PDB	HOMO SAPIENS (HUMAN)	TAL-1, CLASS A BASIC HELIX-LOOP-HELIX PROTEIN 17, BHLHA17, STEM CELL PROTEIN, T-CELL LEUKEMIA/LYMPHOMA PROTEIN 5, SCL
2	B	TRANSCRIPTION FACTOR E2-ALPHA	polymer	82	9674.2	1	UniProt (P15923) Pfam (PF00010) In PDB	HOMO SAPIENS (HUMAN)	CLASS B BASIC HELIX-LOOP-HELIX PROTEIN 21, BHLHB21, IMMUNOGLOBULIN ENHANCER-BINDING FACTOR E12/E47, IMMUNOGLOBULIN TRANSCRIPTION FACTOR 1, KAPPA-E2-BINDING FACTOR, TRANSCRIPTION FACTOR 3, TCF -3, TRANSCRIPTION FACTOR ITF-1, E47
3	E	EBOX FORWARD	polymer	11	3284.2	1		HOMO SAPIENS
4	F	EBOX REVERSE	polymer	11	3422.3	1		HOMO SAPIENS

Sequence modifications

A: 180 - 253 (UniProt: P17542)

PDB	External Database	Details
Met 163	-	expression tag
Gly 164	-	expression tag
Ser 165	-	expression tag
Ser 166	-	expression tag
His 167	-	expression tag
His 168	-	expression tag
His 169	-	expression tag
His 170	-	expression tag
His 171	-	expression tag
His 172	-	expression tag
Ser 173	-	expression tag
Gln 174	-	expression tag
Asp 175	-	expression tag
Pro 176	-	expression tag
Glu 177	-	expression tag
Ile 178	-	expression tag
Ser 179	-	expression tag

B: 535 - 613 (UniProt: P15923)

PDB	External Database	Details
Met 532	-	expression tag
Ala 533	-	expression tag
Asp 534	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	27101.8
All*	Total formula weight	27101.8

*Water molecules are not included.