4KFZ

Crystal structure of LMO2 and anti-LMO2 VH complex

Summary for 4KFZ

Entry DOI	10.2210/pdb4kfz/pdb
Descriptor	LMO-2, Anti-LMO2 VH, ZINC ION (3 entities in total)
Functional Keywords	oncoprotein, t-cell leukemia, proto-oncogene, transcription, developmental protein, lim domain, transcription factor, nucleus
Biological source	Homo sapiens (human) More
Cellular location	Nucleus (Potential): P25791
Total number of polymer chains	4
Total formula weight	63620.93
Authors	Sewell, H.,Tanaka, T.,El Omari, K.,Cruz-Migoni, A.,Mancini, E.J.,Fuentes-Fernandez, N.,Chambers, J.,Rabbitts, T.H. (deposition date: 2013-04-28, release date: 2014-01-22, Last modification date: 2023-09-20)
Primary citation	Sewell, H.,Tanaka, T.,Omari, K.E.,Mancini, E.J.,Cruz, A.,Fernandez-Fuentes, N.,Chambers, J.,Rabbitts, T.H. Conformational flexibility of the oncogenic protein LMO2 primes the formation of the multi-protein transcription complex. Sci Rep, 4:3643-3643, 2014 Cited by PubMed: 24407558 DOI: 10.1038/srep03643 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation