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4ZPK

Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex with HRE DNA

Summary for 4ZPK
Entry DOI10.2210/pdb4zpk/pdb
Related4ZP4 4ZPH 4ZPR
DescriptorAryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, DNA (5'-D(*GP*GP*CP*TP*GP*CP*GP*TP*AP*CP*GP*TP*GP*CP*GP*GP*GP*TP*CP*GP*T)-3'), ... (4 entities in total)
Functional Keywordsarnt, hif-2a, hre, bhlh-pas, protein transport-transcription-dna complex, protein transport/transcription/dna
Biological sourceMus musculus (Mouse)
More
Cellular locationNucleus: P53762 P97481
Total number of polymer chains4
Total formula weight97528.64
Authors
Wu, D.,Potluri, N.,Lu, J.,Kim, Y.,Rastinejad, F. (deposition date: 2015-05-08, release date: 2015-08-12, Last modification date: 2023-09-27)
Primary citationWu, D.,Potluri, N.,Lu, J.,Kim, Y.,Rastinejad, F.
Structural integration in hypoxia-inducible factors.
Nature, 524:303-308, 2015
Cited by
PubMed: 26245371
DOI: 10.1038/nature14883
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.6 Å)
Structure validation

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