4ZPH

Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex with Proflavine

Summary for 4ZPH

• Entry DOI: 10.2210/pdb4zph/pdb
• Related: 4ZP4 4ZPK 4ZPR
• Descriptor: Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, PROFLAVIN, ... (4 entities in total)
• Functional Keywords: hif-2a, arnt, bhlh-pas, proflavine, protein transport-transcription complex, protein transport/transcription
• Biological source: Mus musculus (Mouse); More
• Cellular location: Nucleus: P53762 P97481
• Total number of polymer chains: 4
• Total formula weight: 169485.94

Authors

Wu, D.,Potluri, N.,Lu, J.,Kim, Y.,Rastinejad, F. (deposition date: 2015-05-07, release date: 2015-08-12, Last modification date: 2023-09-27)

• Primary citation: Wu, D.,Potluri, N.,Lu, J.,Kim, Y.,Rastinejad, F.; Structural integration in hypoxia-inducible factors.; Nature, 524:303-308, 2015; PubMed: 26245371; DOI: 10.1038/nature14883

Experimental method

X-RAY DIFFRACTION (2.8 Å)