5EYO

The crystal structure of the Max bHLH domain in complex with 5-carboxyl cytosine DNA

Summary for 5EYO

• Entry DOI: 10.2210/pdb5eyo/pdb
• Descriptor: Protein max, DNA (5'-D(*AP*GP*TP*AP*GP*CP*AP*(1CC)P*GP*TP*GP*CP*TP*AP*CP*T)-3') (3 entities in total)
• Functional Keywords: bhlh protein, 5-carboxylcytosine dna, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 30868.06

Authors

Wang, D.,Hashimoto, H.,Zhang, X.,Cheng, X. (deposition date: 2015-11-25, release date: 2016-12-14, Last modification date: 2023-09-27)

• Primary citation: Wang, D.,Hashimoto, H.,Zhang, X.,Barwick, B.G.,Lonial, S.,Boise, L.H.,Vertino, P.M.,Cheng, X.; MAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myeloma.; Nucleic Acids Res., 45:2396-2407, 2017; PubMed: 27903915; DOI: 10.1093/nar/gkw1184

Experimental method

X-RAY DIFFRACTION (2.39 Å)