Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7RXJ
DownloadVisualize
BU of 7rxj by Molmil
Fab236 in complex with the C-terminal alpha-TSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab236 heavy chain, Fab236 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-23
Release date:2022-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.345 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7S0X
DownloadVisualize
BU of 7s0x by Molmil
Fab352 in complex with the C-terminal alphaTSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab352 heavy chain, Fab352 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-31
Release date:2022-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7RXP
DownloadVisualize
BU of 7rxp by Molmil
Fab1512 in complex with the C-terminal alpha-TSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab1512 heavy chain, Fab1512 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-23
Release date:2022-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.761 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7RXI
DownloadVisualize
BU of 7rxi by Molmil
Fab234 in complex with the C-terminal alpha-TSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab234 heavy chain, Fab234 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-23
Release date:2022-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7RXL
DownloadVisualize
BU of 7rxl by Molmil
Fab1488 in complex with the C-terminal alpha-TSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab1488 heavy chain, Fab1488 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-23
Release date:2022-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.823 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7YYK
DownloadVisualize
BU of 7yyk by Molmil
Crystal structure of the O-fucosylated form of TSRs1-3 from the human thrombospondin 1
Descriptor: 1,2-ETHANEDIOL, Thrombospondin-1, alpha-L-fucopyranose
Authors:Berardinelli, S.J, Eletsky, A, Valero-Gonzalez, J, Ito, A, Manjunath, R, Hurtado-Guerrero, R, Prestegard, J.R, Woods, R.J, Haltiwanger, R.S.
Deposit date:2022-02-18
Release date:2022-05-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:O-fucosylation stabilizes the TSR3 motif in thrombospondin-1 by interacting with nearby amino acids and protecting a disulfide bond.
J.Biol.Chem., 298, 2022
8EH5
DownloadVisualize
BU of 8eh5 by Molmil
Cryo-EM structure of L9 Fab in complex with rsCSP
Descriptor: Circumsporozoite protein, L9 Heavy chain, L9 Light chain
Authors:Martin, G.M, Ward, A.B.
Deposit date:2022-09-13
Release date:2023-06-28
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Structural basis of epitope selectivity and potent protection from malaria by PfCSP antibody L9.
Nat Commun, 14, 2023
8EKA
DownloadVisualize
BU of 8eka by Molmil
Cryo-EM structure of a potent anti-malarial antibody L9 in complex with Plasmodium falciparum circumsporozoite protein (PfCSP)(class 2)
Descriptor: Circumsporozoite protein, L9 Fab heavy chain, L9 Fab light chain
Authors:Tripathi, P, Kwong, P.D.
Deposit date:2022-09-20
Release date:2023-03-15
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structures of anti-malarial antibody L9 with circumsporozoite protein reveal trimeric L9 association and complete 27-residue epitope.
Structure, 31, 2023
8EK1
DownloadVisualize
BU of 8ek1 by Molmil
Cryo-EM structure of a potent anti-malarial antibody L9 in complex with Plasmodium falciparum circumsporozoite protein (PfCSP)(dominant class)
Descriptor: Circumsporozoite protein, L9 Fab heavy chain, L9 Fab light chain
Authors:Tripathi, P, Kwong, P.D.
Deposit date:2022-09-19
Release date:2023-03-15
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures of anti-malarial antibody L9 with circumsporozoite protein reveal trimeric L9 association and complete 27-residue epitope.
Structure, 31, 2023
7B26
DownloadVisualize
BU of 7b26 by Molmil
CirpA1 in complex with pseudo-monomeric Properdin lacking TSR2-3
Descriptor: CirpA1, Properdin, alpha-D-mannopyranose, ...
Authors:Lea, S.M, Johnson, S, Braunger, K.
Deposit date:2020-11-26
Release date:2021-12-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure and function of a family of tick-derived complement inhibitors targeting properdin.
Nat Commun, 13, 2022
2RJQ
DownloadVisualize
BU of 2rjq by Molmil
Crystal structure of ADAMTS5 with inhibitor bound
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, ADAMTS-5, ...
Authors:Mosyak, L, Stahl, M, Somers, W.
Deposit date:2007-10-15
Release date:2007-12-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5.
Protein Sci., 17, 2008
3GHM
DownloadVisualize
BU of 3ghm by Molmil
Crystal structure of the exosite-containing fragment of human ADAMTS13 (form-1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A disintegrin and metalloproteinase with thrombospondin motifs 13, ...
Authors:Akiyama, M, Takeda, S, Kokame, K, Takagi, J, Miyata, T.
Deposit date:2009-03-04
Release date:2009-10-27
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of the non-catalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor
To be Published
3GHN
DownloadVisualize
BU of 3ghn by Molmil
Crystal structure of the exosite-containing fragment of human ADAMTS13 (form-2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A disintegrin and metalloproteinase with thrombospondin motifs 13, ...
Authors:Akiyama, M, Takeda, S, Kokame, K, Takagi, J, Miyata, T.
Deposit date:2009-03-04
Release date:2009-10-27
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of the non-catalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor
To be Published
6OOL
DownloadVisualize
BU of 6ool by Molmil
Structural elucidation of the Ectodomain of mouse UNC5H2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Netrin receptor UNC5B, ...
Authors:Stetefeld, J, McDougall, M.D, Loewen, P.C, Moya, A, Meier, M.
Deposit date:2019-04-23
Release date:2020-04-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural elucidation of the Ectodomain of mouse UNC5H2
To be published
6QIG
DownloadVisualize
BU of 6qig by Molmil
Metalloproteinase
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kim, H.J, Emsley, J.
Deposit date:2019-01-18
Release date:2019-09-04
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure and substrate-induced activation of ADAMTS13.
Nat Commun, 10, 2019
4OKU
DownloadVisualize
BU of 4oku by Molmil
Structure of Toxoplasma gondii proMIC2
Descriptor: Micronemal protein MIC2, alpha-D-mannopyranose
Authors:Song, G, Springer, T.A.
Deposit date:2014-01-22
Release date:2014-03-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structures of the Toxoplasma gliding motility adhesin.
Proc.Natl.Acad.Sci.USA, 111, 2014
4OKR
DownloadVisualize
BU of 4okr by Molmil
Structures of Toxoplasma gondii MIC2
Descriptor: Micronemal protein MIC2, alpha-D-mannopyranose
Authors:Song, G, Springer, T.A.
Deposit date:2014-01-22
Release date:2014-03-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Structures of the Toxoplasma gliding motility adhesin.
Proc.Natl.Acad.Sci.USA, 111, 2014
6MB3
DownloadVisualize
BU of 6mb3 by Molmil
Cryo-EM structure of the circumsporozoite protein of Plasmodium falciparum with a vaccine-elicited antibody reveals maturation of inter-antibody contacts
Descriptor: Fab311 heavy chain, Fab311 light chain, Plasmodium falciparum recombinant shortened CSP
Authors:Cottrell, C.A, Torres, J.L, Ward, A.B.
Deposit date:2018-08-29
Release date:2018-10-31
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Cryo-EM structure ofP. falciparumcircumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts.
Sci Adv, 4, 2018
6MHG
DownloadVisualize
BU of 6mhg by Molmil
Cryo-EM structure of the circumsporozoite protein of Plasmodium falciparum with a vaccine-elicited antibody reveals maturation of inter-antibody contacts
Descriptor: Fab311 heavy chain, Fab311 light chain, circumsporozoite protein
Authors:Cottrell, C.A, Torres, J.L, Ward, A.B.
Deposit date:2018-09-17
Release date:2018-10-31
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:Cryo-EM structure ofP. falciparumcircumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts.
Sci Adv, 4, 2018
5FTT
DownloadVisualize
BU of 5ftt by Molmil
Octameric complex of Latrophilin 3 (Lec, Olf) , Unc5D (Ig, Ig2, TSP1) and FLRT2 (LRR)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADHESION G PROTEIN-COUPLED RECEPTOR L3, CALCIUM ION, ...
Authors:Jackson, V.A, Mehmood, S, Chavent, M, Roversi, P, Carrasquero, M, del Toro, D, Seyit-Bremer, G, Ranaivoson, F.M, Comoletti, D, Sansom, M.S.P, Robinson, C.V, Klein, R, Seiradake, E.
Deposit date:2016-01-15
Release date:2016-05-04
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Super-Complexes of Adhesion Gpcrs and Neural Guidance Receptors
Nat.Commun., 7, 2016
5FOE
DownloadVisualize
BU of 5foe by Molmil
Crystal structure of the C. elegans Protein O-fucosyltransferase 2 (CePOFUT2) double mutant (R298K-R299K) in complex with GDP and the human TSR1 from thrombospondin 1
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, GDP-fucose protein O-fucosyltransferase 2,Thrombospondin-1, ...
Authors:Valero-Gonzalez, J, Leonhard-Melief, C, Lira-Navarrete, E, Jimenez-Oses, G, Hernandez-Ruiz, C, Pallares, M.C, Yruela, I, Vasudevan, D, Lostao, A, Corzana, F, Takeuchi, H, Haltiwanger, R.S, Hurtado-Guerrero, R.
Deposit date:2015-11-19
Release date:2016-01-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:A Proactive Role of Water Molecules in Acceptor Recognition of Thrombospondin Type 1 Repeats by Protein-O-Fucosyltransferase 2
Nat.Chem.Biol., 12, 2016
1W0S
DownloadVisualize
BU of 1w0s by Molmil
Solution structure of trimeric form of properdin by X-ray solution scattering and analytical ultracentrifugation
Descriptor: PROPERDIN
Authors:Sun, Z, Reid, K.B.M, Perkins, S.J.
Deposit date:2004-06-09
Release date:2005-07-06
Method:SOLUTION SCATTERING
Cite:The Dimeric and Trimeric Solution Structures of the Multidomain Complement Protein Properdin by X-Ray Scattering, Analytical Ultracentrifugation and Constrained Modelling.
J.Mol.Biol., 343, 2004
4HQO
DownloadVisualize
BU of 4hqo by Molmil
Crystal structure of Plasmodium vivax TRAP protein
Descriptor: CHLORIDE ION, MAGNESIUM ION, SODIUM ION, ...
Authors:Song, G, Koksal, A.C, Lu, C, Springer, T.A.
Deposit date:2012-10-25
Release date:2012-12-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.194 Å)
Cite:Shape change in the receptor for gliding motility in Plasmodium sporozoites.
Proc.Natl.Acad.Sci.USA, 109, 2012
1W0R
DownloadVisualize
BU of 1w0r by Molmil
Solution structure of dimeric form of properdin by X-ray solution scattering and analytical ultracentrifugation
Descriptor: PROPERDIN
Authors:Sun, Z, Reid, K.B.M, Perkins, S.J.
Deposit date:2004-06-09
Release date:2005-07-06
Method:SOLUTION SCATTERING
Cite:The Dimeric and Trimeric Solution Structures of the Multidomain Complement Protein Properdin by X-Ray Scattering, Analytical Ultracentrifugation and Constrained Modelling.
J.Mol.Biol., 343, 2004
4HQL
DownloadVisualize
BU of 4hql by Molmil
Crystal structure of magnesium-loaded Plasmodium vivax TRAP protein
Descriptor: CHLORIDE ION, MAGNESIUM ION, Sporozoite surface protein 2, ...
Authors:Song, G, Koksal, A.C, Lu, C, Springer, T.A.
Deposit date:2012-10-25
Release date:2012-12-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.241 Å)
Cite:Shape change in the receptor for gliding motility in Plasmodium sporozoites.
Proc.Natl.Acad.Sci.USA, 109, 2012

218853

PDB entries from 2024-04-24

PDB statisticsPDBj update infoContact PDBjnumon