5FTT

Octameric complex of Latrophilin 3 (Lec, Olf) , Unc5D (Ig, Ig2, TSP1) and FLRT2 (LRR)

Summary for 5FTT

Related5FTU
DescriptorNETRIN RECEPTOR UNC5D, LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2, ADHESION G PROTEIN-COUPLED RECEPTOR L3, ... (6 entities in total)
Functional Keywordssignaling protein, signalling protein, leucine-rich repeat, lrr, unc5, unc5d, flrt2, lphn3, lphn, adgrl, adgrl3, adgr, gpcr, uncoordinated-5, netrin receptor, flrt, latrophilin, adhesion, repulsion, guidance, beta propeller, immunoglobulin, thrombospondin, olfactomedin, lectin, octamer
Biological sourceRATTUS NORVEGICUS (NORWAY RAT)
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Cellular locationCell membrane ; Single-pass type I membrane protein  F1LW30
Cell membrane ; Single-pass membrane protein  Q8BLU0
Cell membrane ; Multi-pass membrane protein  Q80TS3
Total number of polymer chains8
Total molecular weight318359.47
Authors
Primary citation
Jackson, V.A.,Mehmood, S.,Chavent, M.,Roversi, P.,Carrasquero, M.,Del Toro, D.,Seyit-Bremer, G.,Ranaivoson, F.M.,Comoletti, D.,Sansom, M.S.P.,Robinson, C.V.,Klein, R.,Seiradake, E.
Super-Complexes of Adhesion Gpcrs and Neural Guidance Receptors
Nat.Commun., 7:11184-, 2016
PubMed: 27091502 (PDB entries with the same primary citation)
DOI: 10.1038/NCOMMS11184
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.4 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.27630.3%2.9%8.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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