5FTT

Octameric complex of Latrophilin 3 (Lec, Olf) , Unc5D (Ig, Ig2, TSP1) and FLRT2 (LRR)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (A, E)	NETRIN RECEPTOR UNC5D	polymer	285	31940.8	2	UniProt (F1LW30) Pfam (PF07679) Pfam (PF00090)	RATTUS NORVEGICUS (NORWAY RAT)	PROTEIN UNC-5 HOMOLOG D, UNC5D
2	B, F (B, F)	LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2	polymer	339	38411.9	2	UniProt (Q8BLU0) Pfam (PF13855) Pfam (PF01463)	MUS MUSCULUS (HOUSE MOUSE)	FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 2, FLRT2
3	C, D, G, H (C, D, G, H)	ADHESION G PROTEIN-COUPLED RECEPTOR L3	polymer	383	43908.0	4	UniProt (Q80TS3) Pfam (PF02140) Pfam (PF02191)	MUS MUSCULUS (HOUSE MOUSE)	LATROPHILIN-3, LECTOMEDIN-3, LPHN3
4	I, J, K, L, Q... (A, B, C, E, F...)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	8	Chemie (NAG)
5	M, O, U, W (C, D, G, H)	SODIUM ION	non-polymer		23.0	4	Chemie (NA)
6	N, P, V, X (C, D, G, H)	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)

Sequence modifications

A, E: 32 - 307 (UniProt: F1LW30)

PDB	External Database	Details
Gly 308	-	expression tag
Thr 309	-	expression tag
Lys 310	-	expression tag
His 311	-	expression tag
His 312	-	expression tag
His 313	-	expression tag
His 314	-	expression tag
His 315	-	expression tag
His 316	-	expression tag

B, F: 35 - 362 (UniProt: Q8BLU0)

PDB	External Database	Details
Thr 33	-	expression tag
Gly 34	-	expression tag
Arg 363	-	expression tag
Thr 364	-	expression tag
Lys 365	-	expression tag
His 366	-	expression tag
His 367	-	expression tag
His 368	-	expression tag
His 369	-	expression tag
His 370	-	expression tag
His 371	-	expression tag

C, D, G, H: 92 - 463 (UniProt: Q80TS3)

PDB	External Database	Details
Thr 90	-	expression tag
Gly 91	-	expression tag
Gly 464	-	expression tag
Thr 465	-	expression tag
Lys 466	-	expression tag
His 467	-	expression tag
His 468	-	expression tag
His 469	-	expression tag
His 470	-	expression tag
His 471	-	expression tag
His 472	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	316337.5
Non-Polymers*	Number of molecules	16
	Total formula weight	2021.9
All*	Total formula weight	318359.5

*Water molecules are not included.