7B26

CirpA1 in complex with pseudo-monomeric Properdin lacking TSR2-3

Summary for 7B26

• Entry DOI: 10.2210/pdb7b26/pdb
• Related: 7B28 7B29 7B2A 7B2D
• Descriptor: Properdin, CirpA1, beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose, ... (6 entities in total)
• Functional Keywords: inhibitor, complement, tick, complex, immunosuppressant
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 64349.33

Authors

Lea, S.M.,Johnson, S.,Braunger, K. (deposition date: 2020-11-26, release date: 2021-12-08, Last modification date: 2024-01-31)

• Primary citation: Braunger, K.,Ahn, J.,Jore, M.M.,Johnson, S.,Tang, T.T.L.,Pedersen, D.V.,Andersen, G.R.,Lea, S.M.; Structure and function of a family of tick-derived complement inhibitors targeting properdin.; Nat Commun, 13:317-317, 2022; PubMed: 35031611; DOI: 10.1038/s41467-021-27920-2

Experimental method

X-RAY DIFFRACTION (3.4 Å)