7B26
CirpA1 in complex with pseudo-monomeric Properdin lacking TSR2-3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Properdin | polymer | 247 | 27484.5 | 1 | UniProt (P27918) Pfam (PF00090) Pfam (PF22195) | Homo sapiens (Human) | Complement factor P |
| 2 | B (A) | Properdin | polymer | 134 | 14485.6 | 1 | UniProt (P27918) Pfam (PF18487) Pfam (PF00090) | Homo sapiens (Human) | Complement factor P;FP head fragment (TB-TSR1) |
| 3 | C (C) | CirpA1 | polymer | 180 | 20431.5 | 1 | UniProt (by SIFTS) (A0A8X6EGU0) | Rhipicephalus pulchellus | |
| 4 | D (D) | beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose | branched | 326.3 | 1 | In PDB GlyTouCan (G36855WW) | |||
| 5 | E, F, G, H, I... (B, A) | alpha-D-mannopyranose | non-polymer | 180.2 | 9 | Chemie (MAN) |
Sequence modifications
B: 256 - 469 (UniProt: P27918)
A: 1 - 134 (UniProt: P27918)
| PDB | External Database | Details |
|---|---|---|
| Met 229 | - | initiating methionine |
| Ile 230 | - | expression tag |
| Thr 231 | - | expression tag |
| Glu 232 | - | expression tag |
| Gly 233 | - | expression tag |
| Ala 234 | - | expression tag |
| Gln 235 | - | expression tag |
| Ala 236 | - | expression tag |
| Pro 237 | - | expression tag |
| Arg 238 | - | expression tag |
| Leu 239 | - | expression tag |
| Leu 240 | - | expression tag |
| Leu 241 | - | expression tag |
| Pro 242 | - | expression tag |
| Pro 243 | - | expression tag |
| Leu 244 | - | expression tag |
| Leu 245 | - | expression tag |
| Leu 246 | - | expression tag |
| Leu 247 | - | expression tag |
| Leu 248 | - | expression tag |
| Thr 249 | - | expression tag |
| Leu 250 | - | expression tag |
| Pro 251 | - | expression tag |
| Ala 252 | - | expression tag |
| Thr 253 | - | expression tag |
| Gly 254 | - | expression tag |
| Ser 255 | - | expression tag |
| His 470 | - | expression tag |
| His 471 | - | expression tag |
| His 472 | - | expression tag |
| His 473 | - | expression tag |
| His 474 | - | expression tag |
| His 475 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 132 | Cys 132 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 62401.6 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 326.3 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1621.4 | |
| All* | Total formula weight | 64349.3 |
