8EKA

Cryo-EM structure of a potent anti-malarial antibody L9 in complex with Plasmodium falciparum circumsporozoite protein (PfCSP)(class 2)

Summary for 8EKA

Entry DOI	10.2210/pdb8eka/pdb
EMDB information	28196
Descriptor	Circumsporozoite protein, L9 Fab heavy chain, L9 Fab light chain (3 entities in total)
Functional Keywords	anti-malarial, pfcsp, immune system
Biological source	Plasmodium falciparum 3D7 More
Total number of polymer chains	7
Total formula weight	182025.56
Authors	Tripathi, P.,Kwong, P.D. (deposition date: 2022-09-20, release date: 2023-03-15, Last modification date: 2023-09-27)
Primary citation	Tripathi, P.,Bender, M.F.,Lei, H.,Da Silva Pereira, L.,Shen, C.H.,Bonilla, B.,Dillon, M.,Ou, L.,Pancera, M.,Wang, L.T.,Zhang, B.,Batista, F.D.,Idris, A.H.,Seder, R.A.,Kwong, P.D. Cryo-EM structures of anti-malarial antibody L9 with circumsporozoite protein reveal trimeric L9 association and complete 27-residue epitope. Structure, 31:480-491.e4, 2023 Cited by PubMed: 36931276 DOI: 10.1016/j.str.2023.02.009 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.7 Å)

Structure validation