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7YYK
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Crystal structure of the O-fucosylated form of TSRs1-3 from the human thrombospondin 1
Descriptor: 1,2-ETHANEDIOL, Thrombospondin-1, alpha-L-fucopyranose
Authors:Berardinelli, S.J, Eletsky, A, Valero-Gonzalez, J, Ito, A, Manjunath, R, Hurtado-Guerrero, R, Prestegard, J.R, Woods, R.J, Haltiwanger, R.S.
Deposit date:2022-02-18
Release date:2022-05-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:O-fucosylation stabilizes the TSR3 motif in thrombospondin-1 by interacting with nearby amino acids and protecting a disulfide bond.
J.Biol.Chem., 298, 2022

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