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3P4L
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BU of 3p4l by Molmil
Crystal structure of a hemojuvelin-binding fragment of neogenin
Descriptor: Neogenin
Authors:Yang, F, West Jr, A.P, Bjorkman, P.J.
Deposit date:2010-10-06
Release date:2010-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of a hemojuvelin-binding fragment of neogenin at 1.8A.
J.Struct.Biol., 174, 2011
4LSD
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BU of 4lsd by Molmil
Myokine structure
Descriptor: Fibronectin type III domain-containing protein 5
Authors:Schumacher, M.A, Ohashi, T, Shah, R.S, Chinnam, N, Erickson, H.
Deposit date:2013-07-22
Release date:2013-10-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:The structure of irisin reveals a novel intersubunit beta-sheet fibronectin type III (FNIII) dimer: implications for receptor activation.
J.Biol.Chem., 288, 2013
4LXO
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BU of 4lxo by Molmil
Crystal structure of 9,10Fn3-elegantin chimera
Descriptor: CALCIUM ION, Fibronectin
Authors:Chang, Y.S, Shiu, J.H, Chuang, W.J.
Deposit date:2013-07-30
Release date:2014-08-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Design, Structure Determination, and Biological Evaluation of Potent Integrin Alpha5beta1-Specific Antagonist Using the Ninth and Tenth Module of Fibronectin Type III Domain
To be Published
4N68
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BU of 4n68 by Molmil
Crystal structure of an internal FN3 domain from human Contactin-5 [PSI-NYSGRC-005804]
Descriptor: Contactin-5, SULFATE ION
Authors:Kumar, P.R, Banu, R, Bhosle, R, Calarese, D.A, Celikgil, A, Chamala, S, Chan, M.K, Chowdhury, S, Fiser, A, Garforth, S.J, Glenn, A.S, Hillerich, B, Khafizov, K, Attonito, J, Love, J.D, Patel, H, Patel, R, Seidel, R.D, Smith, B, Stead, M, Toro, R, Casadevall, A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2013-10-11
Release date:2013-10-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of an internal FN3 domain from human Contactin-5 [PSI-NYSGRC-005804]
to be published
4N5U
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BU of 4n5u by Molmil
Crystal structure of the 4th FN3 domain of human Protein Tyrosine phosphatase, receptor type F [PSI-NYSGRC-006240]
Descriptor: Receptor-type tyrosine-protein phosphatase F, SULFATE ION
Authors:Kumar, P.R, Banu, R, Bhosle, R, Calarese, D.A, Celikgil, A, Chamala, S, Chan, M.K, Chowdhury, S, Fiser, A, Garforth, S.J, Glenn, A.S, Hillerich, B, Khafizov, K, Attonito, J, Love, J.D, Patel, H, Patel, R, Seidel, R.D, Smith, B, Stead, M, Toro, R, Casadevall, A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2013-10-10
Release date:2013-10-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.456 Å)
Cite:Crystal structure of the 4th FN3 domain of human PTP, receptor F [PSI-NYSGRC-006240]
to be published
8C7M
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BU of 8c7m by Molmil
Interleukin 12 receptor subunit beta-1 Fn domains in complex with antagonistic FAb fragment.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, FAb4 Crystal Kappa Light chain, ...
Authors:Bloch, Y, Savvides, S.N.
Deposit date:2023-01-16
Release date:2024-01-31
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
7ZCB
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BU of 7zcb by Molmil
Human Pikachurin/EGFLAM N-terminal Fibronectin-III (1-2) domains
Descriptor: CHLORIDE ION, Pikachurin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Pantalone, S, Savino, S, Viti, L.V, Forneris, F.
Deposit date:2022-03-26
Release date:2023-07-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179.
Sci.Signal., 16, 2023
7ZXK
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BU of 7zxk by Molmil
Human IL-27 in complex with neutralizing SRF388 FAb fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 subunit alpha, Interleukin-27 subunit beta, ...
Authors:Bloch, Y, Skladanowska, K, Strand, J, Welin, M, Logan, D, Hill, J, Savvides, S.N.
Deposit date:2022-05-21
Release date:2022-11-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of activation and antagonism of receptor signaling mediated by interleukin-27.
Cell Rep, 41, 2022
8D7E
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BU of 8d7e by Molmil
Cryo-EM structure of human CNTFR alpha in complex with the Fab fragments of two antibodies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ciliary neurotrophic factor receptor subunit alpha, H4H25311P2 antibody Fab fragment heavy chain, ...
Authors:Zhou, Y, Franklin, M.C.
Deposit date:2022-06-07
Release date:2023-03-29
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Structural insights into the assembly of gp130 family cytokine signaling complexes.
Sci Adv, 9, 2023
8A17
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BU of 8a17 by Molmil
Human PTPRM domains FN3-4, in spacegroup P3221
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase mu, ...
Authors:Shamin, M, Graham, S.C, Sharpe, H.J, Deane, J.E.
Deposit date:2022-05-31
Release date:2023-03-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains.
J.Biol.Chem., 299, 2023
8A16
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BU of 8a16 by Molmil
Human PTPRM domains FN3-4, in spacegroup P212121
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase mu, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Caroe, E, Graham, S.C, Sharpe, H.J, Deane, J.E.
Deposit date:2022-05-31
Release date:2023-03-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains.
J.Biol.Chem., 299, 2023
8AFO
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BU of 8afo by Molmil
Structure of fibronectin 2 and 3 of L1CAM at 2.0 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Neural cell adhesion molecule L1
Authors:Guedez, G, Loew, C.
Deposit date:2022-07-18
Release date:2023-03-08
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:X-ray structure and function of fibronectin domains two and three of the neural cell adhesion molecule L1.
Faseb J., 37, 2023
8AFP
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BU of 8afp by Molmil
Structure of fibronectin 2 and 3 of L1CAM at 3.0 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neural cell adhesion molecule L1
Authors:Guedez, G, Loew, C.
Deposit date:2022-07-18
Release date:2023-03-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-ray structure and function of fibronectin domains two and three of the neural cell adhesion molecule L1.
Faseb J., 37, 2023
8BVO
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BU of 8bvo by Molmil
Titin I110-I111 FnIII tandem from the MIR region (I/A5-I/A6)
Descriptor: Titin
Authors:Mayans, O, Fleming, J.R, Williams, R.
Deposit date:2022-12-05
Release date:2023-02-15
Last modified:2023-03-08
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Immunological and Structural Characterization of Titin Main Immunogenic Region; I110 Domain Is the Target of Titin Antibodies in Myasthenia Gravis.
Biomedicines, 11, 2023
8BW6
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BU of 8bw6 by Molmil
Titin FnIII-domain I110 (I/A6) from the MIR region
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Mayans, O, Fleming, J.R.
Deposit date:2022-12-06
Release date:2023-02-15
Last modified:2023-03-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Immunological and Structural Characterization of Titin Main Immunogenic Region; I110 Domain Is the Target of Titin Antibodies in Myasthenia Gravis.
Biomedicines, 11, 2023
8BNQ
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BU of 8bnq by Molmil
Crystal structure of the FnIII-tandem A84-A86 from the A-band of titin
Descriptor: 1,2-ETHANEDIOL, Titin
Authors:Zacharchenko, T, Fleming, J.R, Mayans, O.
Deposit date:2022-11-14
Release date:2023-04-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular insights into titin's A-band.
J.Muscle Res.Cell.Motil., 44, 2023
8OMW
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BU of 8omw by Molmil
Crystal structure of the titin domain Fn3-20
Descriptor: CHLORIDE ION, Titin
Authors:Rees, M, Gautel, M.
Deposit date:2023-03-31
Release date:2023-08-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation.
J.Struct.Biol., 215, 2023
8OQ9
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BU of 8oq9 by Molmil
Crystal structure of the titin domain Fn3-56
Descriptor: CHLORIDE ION, Titin, ZINC ION
Authors:Rees, M, Gautel, M.
Deposit date:2023-04-11
Release date:2023-08-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation.
J.Struct.Biol., 215, 2023
8OS3
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BU of 8os3 by Molmil
Crystal structure of the titin domain Fn3-11
Descriptor: Titin
Authors:Nikoopour, R, Rees, M, Gautel, M.
Deposit date:2023-04-17
Release date:2023-08-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation.
J.Struct.Biol., 215, 2023
8OIY
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BU of 8oiy by Molmil
Crystal structure of the R15908H missense variant of titin domain Fn3-3
Descriptor: Titin
Authors:Rees, M, Gautel, M.
Deposit date:2023-03-23
Release date:2023-08-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation.
J.Struct.Biol., 215, 2023
8OT5
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BU of 8ot5 by Molmil
Crystal structure of the titin domain Fn3-85
Descriptor: CHLORIDE ION, SODIUM ION, Titin
Authors:Nikoopour, R, Rees, M, Gautel, M.
Deposit date:2023-04-20
Release date:2023-08-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation.
J.Struct.Biol., 215, 2023
8OSD
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BU of 8osd by Molmil
Crystal structure of the titin domain Fn3-49
Descriptor: Titin
Authors:Nikoopour, R, Rees, M, Gautel, M.
Deposit date:2023-04-18
Release date:2023-08-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation.
J.Struct.Biol., 215, 2023
8OTY
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BU of 8oty by Molmil
Crystal structure of the titin domain Fn3-90
Descriptor: Titin
Authors:Nikoopour, R, Rees, M, Gautel, M.
Deposit date:2023-04-21
Release date:2023-08-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation.
J.Struct.Biol., 215, 2023
8ORL
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BU of 8orl by Molmil
Crystal structure of the S23226G missense variant of titin domain Fn3-56
Descriptor: CHLORIDE ION, Titin, ZINC ION
Authors:Rees, M, Gautel, M.
Deposit date:2023-04-14
Release date:2023-08-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation.
J.Struct.Biol., 215, 2023
8ODX
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BU of 8odx by Molmil
Interleukin 12 receptor subunit beta-1 Fn domains in complex with antagonistic FAb4 fragment and VHH.
Descriptor: FAb4 Heavy chain, FAb4 Light chain, Interleukin-12 receptor subunit beta-1, ...
Authors:Bloch, Y, Savvides, S.N.
Deposit date:2023-03-09
Release date:2024-02-07
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024

220113

数据于2024-05-22公开中

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