4LSD

Myokine structure

Summary for 4LSD

• Entry DOI: 10.2210/pdb4lsd/pdb
• Descriptor: Fibronectin type III domain-containing protein 5 (2 entities in total)
• Functional Keywords: myokine, metabolism, hormone
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane; Single-pass type I membrane protein. Irisin: Secreted: Q8NAU1
• Total number of polymer chains: 8
• Total formula weight: 89731.01

Authors

Schumacher, M.A.,Ohashi, T.,Shah, R.S.,Chinnam, N.,Erickson, H. (deposition date: 2013-07-22, release date: 2013-10-16, Last modification date: 2024-04-03)

• Primary citation: Schumacher, M.A.,Chinnam, N.,Ohashi, T.,Shah, R.S.,Erickson, H.P.; The structure of irisin reveals a novel intersubunit beta-sheet fibronectin type III (FNIII) dimer: implications for receptor activation.; J.Biol.Chem., 288:33738-33744, 2013; PubMed: 24114836; DOI: 10.1074/jbc.M113.516641

Experimental method

X-RAY DIFFRACTION (2.28 Å)