8BVO

Titin I110-I111 FnIII tandem from the MIR region (I/A5-I/A6)

Summary for 8BVO

• Entry DOI: 10.2210/pdb8bvo/pdb
• Descriptor: Titin (2 entities in total)
• Functional Keywords: titin, mir, i-band, i/a junction, fniii, ig, structural protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 22248.06

Authors

Mayans, O.,Fleming, J.R.,Williams, R. (deposition date: 2022-12-05, release date: 2023-02-15, Last modification date: 2023-03-08)

• Primary citation: Stergiou, C.,Williams, R.,Fleming, J.R.,Zouvelou, V.,Ninou, E.,Andreetta, F.,Rinaldi, E.,Simoncini, O.,Mantegazza, R.,Bogomolovas, J.,Tzartos, J.,Labeit, S.,Mayans, O.,Tzartos, S.; Immunological and Structural Characterization of Titin Main Immunogenic Region; I110 Domain Is the Target of Titin Antibodies in Myasthenia Gravis.; Biomedicines, 11:-, 2023; PubMed: 36830985; DOI: 10.3390/biomedicines11020449

Experimental method

X-RAY DIFFRACTION (2.55 Å)