PDB: 6405 resultsInfo pagesStatus searchChemie searchBIRD

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6UZO	HLA-B*15:02 complexed with a synthetic peptide Descriptor: Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ... Authors: Schutte, R.J, Li, D, Ostrov, D.A. Deposit date: 2019-11-15 Release date: 2020-11-18 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.349 Å) Cite: HLA-B*15:02 complexed with a synthetic peptide To Be Published
6UZ1	Noncanonical binding of single-chain A6 TCR variant S3-4 in complex with Tax/HLA-A2 Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-2-microglobulin, LEU-LEU-PHE-GLY-TYR-PRO-VAL-TYR-VAL, ... Authors: Ma, J, Singh, N.K. Deposit date: 2019-11-14 Release date: 2020-10-28 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.14 Å) Cite: An Engineered T Cell Receptor Variant Realizes the Limits of Functional Binding Modes. Biochemistry, 59, 2020
2BNQ	Structural and kinetic basis for heightened immunogenicity of T cell vaccines Descriptor: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, SYNTHETIC PEPTIDE, ... Authors: Chen, J.-L, Stewart-Jones, G, Bossi, G, Lissin, N.M, Wooldridge, L, Choi, E.M.L, Held, G, Dunbar, P.R, Esnouf, R.M, Sami, M, Boultier, J.M, Rizkallah, P.J, Renner, C, Sewell, A, van der Merwe, P.A, Jackobsen, B.K, Griffiths, G, Jones, E.Y, Cerundolo, V. Deposit date: 2005-03-31 Release date: 2005-05-23 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural and Kinetic Basis for Heightened Immunogenicity of T Cell Vaccines J.Exp.Med., 201, 2005
6V2O	HLA-B*57:01 presenting the peptide ASLNLPAVSW Descriptor: ACETATE ION, Beta-2-microglobulin, MHC class I antigen, ... Authors: Maclachlan, B, Rossjohn, J, Vivian, J.P. Deposit date: 2019-11-25 Release date: 2020-05-20 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.27 Å) Cite: The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function. Proc.Natl.Acad.Sci.USA, 117, 2020
6V80	Crystal structure of human CD1d presenting alpha-Galactosylceramide in complex with NKT12 TCR and VHH nanobody 1D12 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ... Authors: Shahine, A, Rossjohn, J. Deposit date: 2019-12-10 Release date: 2020-09-16 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.53 Å) Cite: A single-domain bispecific antibody targeting CD1d and the NKT T-cell receptor induces a potent antitumor response. Nat Cancer, 2020
2BNR	Structural and kinetic basis for heightened immunogenicity of T cell vaccines Descriptor: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, SYNTHETIC PEPTIDE, ... Authors: Chen, J.-L, Stewart-Jones, G, Bossi, G, Lissin, N.M, Wooldridge, L, Choi, E.M.L, Held, G, Dunbar, P.R, Esnouf, R.M, Sami, M, Boultier, J.M, Rizkallah, P.J, Renner, C, Sewell, A, van der Merwe, P.A, Jackobsen, B.K, Griffiths, G, Jones, E.Y, Cerundolo, V. Deposit date: 2005-03-31 Release date: 2005-05-23 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural and Kinetic Basis for Heightened Immunogenicity of T Cell Vaccines J.Exp.Med., 201, 2005
6UZN	HLA-B*15:02 complexed with a synthetic peptide Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Beta-2-microglobulin, ... Authors: Schutte, R.J, Li, D, Ostrov, D.A. Deposit date: 2019-11-15 Release date: 2020-11-18 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.22 Å) Cite: HLA-B*15:02 complexed with a synthetic peptide To Be Published
6UZS	HLA-B*15:01 complexed with a synthetic peptide Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Beta-2-microglobulin, ... Authors: Schutte, R.J, Li, D, Ostrov, D.A. Deposit date: 2019-11-15 Release date: 2020-11-18 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.9 Å) Cite: HLA-B*15:02 complexed with a synthetic peptide To Be Published
6V2P	HLA-B*57:03 presenting the peptide ASLNLPAVSW Descriptor: ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... Authors: Maclachlan, B, Rossjohn, J, Vivian, J.P. Deposit date: 2019-11-25 Release date: 2020-05-20 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.3 Å) Cite: The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function. Proc.Natl.Acad.Sci.USA, 117, 2020
6VB1	HLA-B*15:02 complexed with a synthetic peptide Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... Authors: Schutte, R.J, Li, D, Andring, J, McKenna, R, Ostrov, D.A. Deposit date: 2019-12-18 Release date: 2020-11-25 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.75 Å) Cite: HLA-B*15:02 complexed with a synthetic peptide To Be Published
6VB7	HLA-B*15:02 complexed with a synthetic peptide Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Beta-2-microglobulin, ... Authors: Schutte, R.J, Li, D, Ostrov, D.A. Deposit date: 2019-12-18 Release date: 2020-11-25 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.1 Å) Cite: HLA-B*15:02 complexed with a synthetic peptide To Be Published
6VB6	HLA-B*15:02 complexed with a synthetic peptide Descriptor: ACETATE ION, Beta-2-microglobulin, GLYCEROL, ... Authors: Schutte, R.J, Li, D, Ostrov, D.A. Deposit date: 2019-12-18 Release date: 2020-11-25 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.15 Å) Cite: HLA-B*15:02 complexed with a synthetic peptide To Be Published
6VM7	SILv44 T cell receptor bound to HLA-A2 presenting gp100 peptide (ITDQVPFSV) Descriptor: Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ... Authors: Smith, A.R, Baker, B.M. Deposit date: 2020-01-27 Release date: 2021-01-20 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.41 Å) Cite: Structurally silent peptide anchor modifications allosterically modulate T cell recognition in a receptor-dependent manner Proc.Natl.Acad.Sci.USA, 118, 2021
6VQO	T cell receptor-p53-HLA-A2 complex Descriptor: Beta-2-microglobulin, MHC class I antigen, T-cell receptor 1a2, ... Authors: Wu, D, Gallagher, D.T, Pierce, B.G, Mariuzza, R.A. Deposit date: 2020-02-05 Release date: 2020-06-17 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen. Nat Commun, 11, 2020
6VR1	Complex of HLA-A2, a class I MHC, with a p53 peptide Descriptor: Beta-2-microglobulin, Cellular tumor antigen p53 peptide, MHC class I antigen Authors: Wu, D, Pierce, B.G, Gallagher, D.T, Mariuzza, R.A. Deposit date: 2020-02-06 Release date: 2020-06-10 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.37 Å) Cite: Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen. Nat Commun, 11, 2020
2C7U	Conflicting selective forces affect CD8 T-cell receptor contact sites in an HLA-A2 immunodominant HIV epitope. Descriptor: BETA-2-MICROGLOBULIN, GAG PROTEIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... Authors: Iversen, A.K, Stewart-Jones, G, Learn, G.H, Christie, N, Sylvester-Hviid, C, Armitage, A.E, Kaul, R, Beattie, T, Lee, J.K, Li, Y, Chotiyarnwong, P, Dong, T, Xu, X, Luscher, M.A, MacDonald, K, Ullum, H, Klarlund-Pedersen, B, Skinhoj, P, Fugger, J.L, Buus, S, Mullins, J.I, Jones, E.Y, van der Merwe, P.A, McMichael, A.J. Deposit date: 2005-11-29 Release date: 2006-03-08 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.38 Å) Cite: Conflicting Selective Forces Affect T Cell Receptor Contacts in an Immunodominant Human Immunodeficiency Virus Epitope. Nat.Immunol., 7, 2006
6VMA	T4H2 T cell receptor bound to HLA-A2 presenting gp100 peptide (ITDQVPFSV) Descriptor: Beta-2-microglobulin, MHC class I antigen, A-2 alpha chain, ... Authors: Smith, A.R, Baker, B.M. Deposit date: 2020-01-27 Release date: 2021-01-20 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Structurally silent peptide anchor modifications allosterically modulate T cell recognition in a receptor-dependent manner Proc.Natl.Acad.Sci.USA, 118, 2021
6VM9	T4H2 T cell receptor bound to HLA-A2 presenting gp100T2M peptide (IMDQVPFSV) Descriptor: Beta-2-microglobulin, MHC class I antigen, A-2 alpha chain, ... Authors: Smith, A.R, Baker, B.M. Deposit date: 2020-01-27 Release date: 2021-01-20 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structurally silent peptide anchor modifications allosterically modulate T cell recognition in a receptor-dependent manner Proc.Natl.Acad.Sci.USA, 118, 2021
6VRN	T cell receptor-p53-HLA-A2 complex Descriptor: Beta-2-microglobulin, Cellular tumor antigen p53 peptide, MHC class I antigen, ... Authors: Wu, D, Gallagher, D.T, Gowthaman, R, Pierce, B.G, Mariuzza, R.A. Deposit date: 2020-02-08 Release date: 2020-06-17 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.46 Å) Cite: Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen. Nat Commun, 11, 2020
6ULN	Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation Descriptor: Beta-2-microglobulin, GLY-ALA-ASP-GLY-VAL-GLY-LYS-SER-ALA, GLYCEROL, ... Authors: Sun, P.D, Sim, M.J.W. Deposit date: 2019-10-08 Release date: 2020-05-27 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.01 Å) Cite: High-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D. Proc.Natl.Acad.Sci.USA, 117, 2020
6VIU	HLA-B*15:02 complexed with a synthetic peptide Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Beta-2-microglobulin, ... Authors: Schutte, R.J, Li, D, Ostrov, D.A. Deposit date: 2020-01-14 Release date: 2020-11-25 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.334 Å) Cite: HLA-B*15:02 complexed with a synthetic peptide To Be Published
6VRM	T cell receptor-p53-HLA-A2 complex Descriptor: Beta-2-microglobulin, Cellular tumor antigen p53 peptide, MHC class I antigen, ... Authors: Wu, D, Gallagher, D.T, Gowthaman, R, Pierce, B.G, Mariuzza, R.A. Deposit date: 2020-02-08 Release date: 2020-06-17 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.61 Å) Cite: Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen. Nat Commun, 11, 2020
6VMX	Structure of HD14 TCR in complex with HLA-B7 presenting an EBV epitope Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... Authors: Farenc, C, Rossjohn, J, Gras, S. Deposit date: 2020-01-28 Release date: 2020-07-29 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.1 Å) Cite: A Shared TCR Bias toward an Immunogenic EBV Epitope Dominates in HLA-B*07:02-Expressing Individuals. J Immunol., 205, 2020
6VM8	SILv44 T cell receptor bound to HLA-A2 presenting gp100T2M peptide (IMDQVPFSV) Descriptor: Beta-2-microglobulin, CITRATE ANION, MHC class I antigen, ... Authors: Smith, A.R, Baker, B.M. Deposit date: 2020-01-27 Release date: 2020-11-25 Last modified: 2021-06-09 Method: X-RAY DIFFRACTION (2.41 Å) Cite: Structurally silent peptide anchor modifications allosterically modulate T cell recognition in a receptor-dependent manner. Proc.Natl.Acad.Sci.USA, 118, 2021
6VMC	T4H2 T cell receptor bound to HLA-A2 presenting gp100T2L peptide (ILDQVPFSV) Descriptor: Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ... Authors: Smith, A.R, Baker, B.M. Deposit date: 2020-01-27 Release date: 2021-01-20 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Structurally silent peptide anchor modifications allosterically modulate T cell recognition in a receptor-dependent manner Proc.Natl.Acad.Sci.USA, 118, 2021

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