6VM8
SILv44 T cell receptor bound to HLA-A2 presenting gp100T2M peptide (IMDQVPFSV)
Summary for 6VM8
| Entry DOI | 10.2210/pdb6vm8/pdb |
| Descriptor | MHC class I antigen, A-2 alpha chain, SILv44 T cell receptor beta chain, SILv44 T cell receptor alpha chain, ... (7 entities in total) |
| Functional Keywords | tcr, mhc class i, hla a2, autoimmune, vitiligo, melanoma, immune system |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 5 |
| Total formula weight | 95937.69 |
| Authors | Smith, A.R.,Baker, B.M. (deposition date: 2020-01-27, release date: 2020-11-25, Last modification date: 2021-06-09) |
| Primary citation | Smith, A.R.,Alonso, J.A.,Ayres, C.M.,Singh, N.K.,Hellman, L.M.,Baker, B.M. Structurally silent peptide anchor modifications allosterically modulate T cell recognition in a receptor-dependent manner. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 33468649DOI: 10.1073/pnas.2018125118 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.41 Å) |
Structure validation
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