6VM8
SILv44 T cell receptor bound to HLA-A2 presenting gp100T2M peptide (IMDQVPFSV)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | MHC class I antigen, A-2 alpha chain | polymer | 275 | 31854.2 | 1 | UniProt (A0A5B8RNS7) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (A0A140T913) | Homo sapiens (Human) | |
| 2 | B (E) | SILv44 T cell receptor beta chain | polymer | 243 | 27692.8 | 1 | Homo sapiens (Human) | ||
| 3 | C (D) | SILv44 T cell receptor alpha chain | polymer | 208 | 23287.0 | 1 | Homo sapiens (Human) | ||
| 4 | D (B) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 5 | E (C) | Melanocyte protein PMEL | polymer | 9 | 1035.2 | 1 | UniProt (P40967) | Homo sapiens | ME20-M,ME20M,Melanocyte protein Pmel 17,Melanocytes lineage-specific antigen GP100,Melanoma-associated ME20 antigen,P1,P100,Premelanosome protein,Silver locus protein homolog |
| 6 | F (D) | CITRATE ANION | non-polymer | 189.1 | 1 | Chemie (FLC) | |||
| 7 | G, H, I, J, K (A, E, D, B, C) | water | water | 18.0 | 89 | Chemie (HOH) |
Sequence modifications
B: 2 - 100 (UniProt: P61769)
C: 1 - 9 (UniProt: P40967)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Met 2 | Thr 210 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 95748.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 189.1 | |
| All* | Total formula weight | 95937.7 |
