6VRN

T cell receptor-p53-HLA-A2 complex

Summary for 6VRN

• Entry DOI: 10.2210/pdb6vrn/pdb
• Related: 6vqo 6vr1 6vr5 6vrm
• Descriptor: MHC class I antigen, Beta-2-microglobulin, T-cell receptor 38-10, alfa chain, ... (6 entities in total)
• Functional Keywords: tcr complex, mhc, hla, adoptive cell therapy, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 98427.16

Authors

Wu, D.,Gallagher, D.T.,Gowthaman, R.,Pierce, B.G.,Mariuzza, R.A. (deposition date: 2020-02-08, release date: 2020-06-17, Last modification date: 2023-10-11)

• Primary citation: Wu, D.,Gallagher, D.T.,Gowthaman, R.,Pierce, B.G.,Mariuzza, R.A.; Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen.; Nat Commun, 11:2908-2908, 2020; PubMed: 32518267; DOI: 10.1038/s41467-020-16755-y

Experimental method

X-RAY DIFFRACTION (2.46 Å)