6VM9

T4H2 T cell receptor bound to HLA-A2 presenting gp100T2M peptide (IMDQVPFSV)

Summary for 6VM9

Entry DOI	10.2210/pdb6vm9/pdb
Descriptor	MHC class I antigen, A-2 alpha chain, Beta-2-microglobulin, Melanocyte protein PMEL, ... (5 entities in total)
Functional Keywords	tcr, mhc class i, hla a2, melanoma, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	5
Total formula weight	94965.24
Authors	Smith, A.R.,Baker, B.M. (deposition date: 2020-01-27, release date: 2021-01-20, Last modification date: 2023-10-11)
Primary citation	Smith, A.R.,Alonso, J.A.,Ayres, C.M.,Singh, N.K.,Hellman, L.M.,Baker, B.M. Structurally silent peptide anchor modifications allosterically modulate T cell recognition in a receptor-dependent manner Proc.Natl.Acad.Sci.USA, 118:e2018125118-, 2021 Cited by DOI: 10.1073/pnas.2018125118 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation