PDB: 45953 resultsInfo pagesStatus searchChemie searchBIRD

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4N95	E. coli sliding clamp in complex with 5-chloroindoline-2,3-dione Descriptor: 5-chloro-1H-indole-2,3-dione, CALCIUM ION, CHLORIDE ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-10-19 Release date: 2013-11-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
1UOL	Crystal structure of the human p53 core domain mutant M133L/V203A/N239Y/N268D at 1.9 A resolution. Descriptor: CELLULAR TUMOR ANTIGEN P53, ZINC ION Authors: Joerger, A.C, Allen, M.D, Fersht, A.R. Deposit date: 2003-09-19 Release date: 2003-10-16 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal Structure of a Superstable Mutant of Human P53 Core Domain. Insights Into the Mechanism of Rescuing Oncogenic Mutations J.Biol.Chem., 279, 2004
2L4A	NMR structure of the DNA-binding domain of E.coli Lrp Descriptor: Leucine responsive regulatory protein Authors: Kawamura, T, Zhou, H, Dahlquist, F.W. Deposit date: 2010-10-01 Release date: 2011-03-09 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: The design involved in PapI and Lrp regulation of the pap operon. J.Mol.Biol., 409, 2011
7V97	Arsenic-bound p53 DNA-binding domain mutant V272M Descriptor: ARSENIC, Cellular tumor antigen p53, ZINC ION Authors: Lu, M, Xing, Y.F, Wang, Z.Y, Ni, Y, Song, H.X. Deposit date: 2021-08-24 Release date: 2022-08-31 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Diverse rescue potencies of p53 mutations to ATO are predetermined by intrinsic mutational properties. Sci Transl Med, 15, 2023
5N9F	Crystal Structure of Drosophila DHX36 helicase in complex with ssDNA CpG_A Descriptor: CG9323, isoform A, CHLORIDE ION, ... Authors: Chen, W.-F, Rety, S, Hai-Lei Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. Deposit date: 2017-02-24 Release date: 2018-03-21 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.969 Å) Cite: Structural and mechanistic insights into DHX36-mediated innate immunity and G-quadruplex unfolding To Be Published
7XRC	Crystal Structure of the dimeric Brn2 (Pou3f2) POU domain bound to palindromic MORE DNA Descriptor: More palindromic Oct factor Recognition Element (MORE), POU domain protein Authors: Tan, D.S.Y, Jauch, R. Deposit date: 2022-05-10 Release date: 2022-06-15 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.89 Å) Cite: The homeodomain of Oct4 is a dimeric binder of methylated CpG elements. Nucleic Acids Res., 51, 2023
1GDT	CRYSTAL STRUCTURE OF A SITE-SPECIFIC RECOMBINASE, GAMMA-DELTA RESOLVASE COMPLEXED WITH A 34 BP CLEAVAGE SITE Descriptor: PROTEIN (GAMMA DELTA RESOLVASE), SITE I OF RES DNA Authors: Yang, W, Steitz, T.A. Deposit date: 1995-04-11 Release date: 1996-04-03 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (3 Å) Cite: Crystal structure of the site-specific recombinase gamma delta resolvase complexed with a 34 bp cleavage site. Cell(Cambridge,Mass.), 82, 1995
1H38	Structure of a T7 RNA polymerase elongation complex at 2.9A resolution Descriptor: 5'-D(*GP*GP*GP*AP*AP*TP*CP*GP*AP*CP *AP*TP*CP*GP*CP*CP*GP*C)-3', 5'-D(*GP*TP*CP*GP*AP*TP*TP*CP*CP*CP)-3', 5'-R(*AP*AP*CP*UP*GP*CP*GP*GP*CP*GP *AP*U)-3', ... Authors: Tahirov, T.H, Temyakov, D, Anikin, M, Patlan, V, McAllister, W.T, Vassylyev, D.G, Yokoyama, S. Deposit date: 2002-08-24 Release date: 2002-11-20 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structure of a T7 RNA Polymerase Elongation Complex at 2.9 A Resolution Nature, 420, 2002
5GKS	Crystal structure of SLE patient-derived anti-DNA antibody Descriptor: IgG2, Fab (heavy chain), PHOSPHATE ION, ... Authors: Arimori, T, Sakakibara, S, Kikutani, H, Takagi, J. Deposit date: 2016-07-05 Release date: 2017-07-05 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus Sci Rep, 7, 2017
4I6R	High Resolution Crystal Structure of the Wild-Type Restriction-Modification Controller Protein C.Esp1396I (Triclinic form) Descriptor: GLYCEROL, Regulatory protein, SULFATE ION Authors: Martin, R.N.A, McGeehan, J.E, Kneale, G.G. Deposit date: 2012-11-30 Release date: 2013-11-13 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.38 Å) Cite: Structural and Mutagenic Analysis of the RM Controller Protein C.Esp1396I. Plos One, 9, 2014
8JKL	IRF4 DNA-binding domain bound to an DNA containing GATA motif Descriptor: GATA-Forward, GATA-Reverse, Interferon regulatory factor 4 Authors: Wang, G, Feng, X, Ding, J. Deposit date: 2023-06-01 Release date: 2023-09-20 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.94 Å) Cite: Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency. Structure, 31, 2023
8JKQ	T95R mutant IRF4 DNA-binding domain bound to an DNA containing GACA motif Descriptor: GACA-Forward, GACA-Reverse, Interferon regulatory factor 4 Authors: Wang, G, Feng, X, Ding, J. Deposit date: 2023-06-01 Release date: 2023-09-20 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (3.09 Å) Cite: Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency. Structure, 31, 2023
4IA8	Crystal Structure of a Y37A mutant of the Restriction-Modification Controller Protein C.Esp1396I Descriptor: Regulatory protein, SULFATE ION Authors: Martin, R.N.A, McGeehan, J.E, Kneale, G.G. Deposit date: 2012-12-06 Release date: 2013-12-11 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structural and Mutagenic Analysis of the RM Controller Protein C.Esp1396I. Plos One, 9, 2014
8JKN	T95R mutant IRF4 DNA-binding domain bound to an DNA containing GAAA motif Descriptor: GAAA-Forward, GAAA-Reverse, Interferon regulatory factor 4 Authors: Wang, G, Feng, X, Ding, J. Deposit date: 2023-06-01 Release date: 2023-09-20 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.92 Å) Cite: Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency. Structure, 31, 2023
8JKO	T95R mutant IRF4 DNA-binding domain bound to an DNA containing GATA motif Descriptor: GATA-Forward, GATA-Reverse, Interferon regulatory factor 4 Authors: Wang, G, Feng, X, Ding, J. Deposit date: 2023-06-01 Release date: 2023-09-20 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency. Structure, 31, 2023
1FBU	HEAT SHOCK TRANSCRIPTION FACTOR DNA BINDING DOMAIN Descriptor: HEAT SHOCK FACTOR PROTEIN Authors: Hardy, J.A, Nelson, H.C.M. Deposit date: 2000-07-16 Release date: 2001-01-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Proline in alpha-helical kink is required for folding kinetics but not for kinked structure, function, or stability of heat shock transcription factor. Protein Sci., 9, 2000
1FBQ	HEAT SHOCK TRANSCRIPTION FACTOR DNA BINDING DOMAIN CONTAINING THE P237K MUTATION Descriptor: HEAT SHOCK FACTOR PROTEIN Authors: Hardy, J.A, Nelson, H.C.M. Deposit date: 2000-07-16 Release date: 2001-01-17 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Proline in alpha-helical kink is required for folding kinetics but not for kinked structure, function, or stability of heat shock transcription factor. Protein Sci., 9, 2000
8JKS	T95R mutant IRF4 DNA-binding domain bound to an DNA containing GAGA motif Descriptor: GAGA-Forward, GAGA-Reverse, Interferon regulatory factor 4 Authors: Wang, G, Feng, X, Ding, J. Deposit date: 2023-06-01 Release date: 2023-09-20 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency. Structure, 31, 2023
4I6U	Crystal Structure of a Y37F mutant of the Restriction-Modification Controller Protein C.Esp1396I Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Martin, R.N.A, McGeehan, J.E, Kneale, G.G. Deposit date: 2012-11-30 Release date: 2013-11-13 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Structural and Mutagenic Analysis of the RM Controller Protein C.Esp1396I. Plos One, 9, 2014
4I6T	Crystal Structure of a T36A mutant of the Restriction-Modification Controller Protein C.Esp1396I Descriptor: MALONATE ION, Regulatory protein Authors: Martin, R.N.A, McGeehan, J.E, Kneale, G.G. Deposit date: 2012-11-30 Release date: 2013-11-13 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural and Mutagenic Analysis of the RM Controller Protein C.Esp1396I. Plos One, 9, 2014
4CSR	High resolution crystal structure of the histone fold dimer (NF-YB)-(NF-YC) Descriptor: GLYCEROL, NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA, NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT GAMMA Authors: Gnesutta, N, Cocolo, S, Mantovani, R, Bolognesi, M, Nardini, M. Deposit date: 2014-03-09 Release date: 2015-03-18 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: High Resolution Crystal Structure of the Histone Fold Dimer (NF-Yb)-(NF-Yc) To be Published
1ENH	STRUCTURAL STUDIES OF THE ENGRAILED HOMEODOMAIN Descriptor: ENGRAILED HOMEODOMAIN Authors: Clarke, N.D, Kissinger, C.R, Desjarlais, J, Gilliland, G.L, Pabo, C.O. Deposit date: 1994-05-20 Release date: 1994-08-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural studies of the engrailed homeodomain. Protein Sci., 3, 1994
7SVU	TnsBctd-TnsC-TniQ complex Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (28-MER), DNA (29-MER), ... Authors: Park, J, Tsai, A.W.T, Kellogg, E.H. Deposit date: 2021-11-19 Release date: 2022-11-23 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structures of the holo CRISPR RNA-guided transposon integration complex Nature, 613, 2023
7PT7	Structure of MCM2-7 DH complexed with Cdc7-Dbf4 in the presence of ADP:BeF3, state I Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division control protein 7, ... Authors: Saleh, A, Noguchi, Y, Aramayo, R, Ivanova, M.E, Speck, C. Deposit date: 2021-09-26 Release date: 2022-06-08 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: The structural basis of Cdc7-Dbf4 kinase dependent targeting and phosphorylation of the MCM2-7 double hexamer. Nat Commun, 13, 2022
7PT6	Structure of MCM2-7 DH complexed with Cdc7-Dbf4 in the presence of ATPgS, state III Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 7, DDK kinase regulatory subunit DBF4, ... Authors: Saleh, A, Noguchi, Y, Aramayo, R, Ivanova, M.E, Speck, C. Deposit date: 2021-09-26 Release date: 2022-06-08 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: The structural basis of Cdc7-Dbf4 kinase dependent targeting and phosphorylation of the MCM2-7 double hexamer. Nat Commun, 13, 2022

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