7PT7
Structure of MCM2-7 DH complexed with Cdc7-Dbf4 in the presence of ADP:BeF3, state I
This is a non-PDB format compatible entry.
Summary for 7PT7
Entry DOI | 10.2210/pdb7pt7/pdb |
EMDB information | 13620 |
Descriptor | Undefined Mcm4 flexible N-terminal tail, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (13 entities in total) |
Functional Keywords | helicase, activation, kinase, phosphorylation, replication |
Biological source | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More |
Total number of polymer chains | 15 |
Total formula weight | 1359453.04 |
Authors | Saleh, A.,Noguchi, Y.,Aramayo, R.,Ivanova, M.E.,Speck, C. (deposition date: 2021-09-26, release date: 2022-06-08, Last modification date: 2024-07-17) |
Primary citation | Saleh, A.,Noguchi, Y.,Aramayo, R.,Ivanova, M.E.,Stevens, K.M.,Montoya, A.,Sunidhi, S.,Carranza, N.L.,Skwark, M.J.,Speck, C. The structural basis of Cdc7-Dbf4 kinase dependent targeting and phosphorylation of the MCM2-7 double hexamer. Nat Commun, 13:2915-2915, 2022 Cited by PubMed: 35614055DOI: 10.1038/s41467-022-30576-1 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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