7XRC

Crystal Structure of the dimeric Brn2 (Pou3f2) POU domain bound to palindromic MORE DNA

Summary for 7XRC

Entry DOI	10.2210/pdb7xrc/pdb
Descriptor	POU domain protein, More palindromic Oct factor Recognition Element (MORE), ... (4 entities in total)
Functional Keywords	pou family, transcription-dna complex, transcription/dna
Biological source	Mus More
Total number of polymer chains	3
Total formula weight	25132.50
Authors	Tan, D.S.Y.,Jauch, R. (deposition date: 2022-05-10, release date: 2022-06-15, Last modification date: 2023-11-29)
Primary citation	Tan, D.S.,Cheung, S.L.,Gao, Y.,Weinbuch, M.,Hu, H.,Shi, L.,Ti, S.C.,Hutchins, A.P.,Cojocaru, V.,Jauch, R. The homeodomain of Oct4 is a dimeric binder of methylated CpG elements. Nucleic Acids Res., 51:1120-1138, 2023 Cited by PubMed: 36631980 DOI: 10.1093/nar/gkac1262 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.89 Å)

Structure validation