7XRC

Crystal Structure of the dimeric Brn2 (Pou3f2) POU domain bound to palindromic MORE DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
C	0003677	molecular_function	DNA binding
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PROSITE/UniProt

site_id	PS00027
Number of Residues	24
Details	HOMEOBOX_1 'Homeobox' domain signature. LAdsLqLEkeVVRVWFcNrrqkeK

Chain	Residue	Details
C	LEU534-LYS557

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site_id	PS00035
Number of Residues	13
Details	POU_1 POU-specific (POUs) domain signature 1. RRIkLGFtQaDVG

Chain	Residue	Details
C	ARG263-GLY275

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site_id	PS00465
Number of Residues	14
Details	POU_2 POU-specific (POUs) domain signature 2. SQTTICRFEaLqLS

Chain	Residue	Details
C	SER287-SER300

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	59
Details	DNA_BIND: Homeobox => ECO:0000255|PROSITE-ProRule:PRU00108

Chain	Residue	Details
C	LYS501-THR560

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332

Chain	Residue	Details
C	SER488

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