7PT6

Structure of MCM2-7 DH complexed with Cdc7-Dbf4 in the presence of ATPgS, state III

This is a non-PDB format compatible entry.

Summary for 7PT6

• Entry DOI: 10.2210/pdb7pt6/pdb
• EMDB information: 13619
• Descriptor: Undefined Mcm4 flexible N-terminal tail, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... (13 entities in total)
• Functional Keywords: helicase, activation, kinase, phosphorylation, replication
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Total number of polymer chains: 18
• Total formula weight: 1501129.69

Authors

Saleh, A.,Noguchi, Y.,Aramayo, R.,Ivanova, M.E.,Speck, C. (deposition date: 2021-09-26, release date: 2022-06-08)

• Primary citation: Saleh, A.,Noguchi, Y.,Aramayo, R.,Ivanova, M.E.,Stevens, K.M.,Montoya, A.,Sunidhi, S.,Carranza, N.L.,Skwark, M.J.,Speck, C.; The structural basis of Cdc7-Dbf4 kinase dependent targeting and phosphorylation of the MCM2-7 double hexamer.; Nat Commun, 13:2915-2915, 2022; PubMed: 35614055; DOI: 10.1038/s41467-022-30576-1

Experimental method

ELECTRON MICROSCOPY (3.2 Å)