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2DFK
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BU of 2dfk by Molmil
Crystal structure of the CDC42-Collybistin II complex
Descriptor: GLYCEROL, SULFATE ION, cell division cycle 42 isoform 1, ...
Authors:Xiang, S, Kim, E.Y, Connelly, J.J, Nassar, N, Kirsch, J, Winking, J, Schwarz, G, Schindelin, H.
Deposit date:2006-03-02
Release date:2006-05-02
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The Crystal Structure of Cdc42 in Complex with Collybistin II, a Gephyrin-interacting Guanine Nucleotide Exchange Factor.
J.Mol.Biol., 359, 2006
2ASE
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BU of 2ase by Molmil
NMR structure of the F28L mutant of Cdc42Hs
Descriptor: Cell division control protein 42 homolog
Authors:Adams, P.D, Oswald, R.E.
Deposit date:2005-08-23
Release date:2006-02-21
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution Structure of an Oncogenic Mutant of Cdc42Hs
Biochemistry, 45, 2006
7CFD
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BU of 7cfd by Molmil
Drosophila melanogaster Krimper eTud2-AubR15me2 complex
Descriptor: FI20010p1, Protein aubergine
Authors:Hu, H, Li, S.
Deposit date:2020-06-25
Release date:2021-06-02
Last modified:2021-09-15
Method:X-RAY DIFFRACTION (2.704 Å)
Cite:Binding of guide piRNA triggers methylation of the unstructured N-terminal region of Aub leading to assembly of the piRNA amplification complex.
Nat Commun, 12, 2021
7CFC
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BU of 7cfc by Molmil
Drosophila melanogaster Krimper eTud1-Ago3 complex
Descriptor: FI20010p1, Protein argonaute-3
Authors:Hu, H, Li, S.
Deposit date:2020-06-25
Release date:2021-06-02
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Binding of guide piRNA triggers methylation of the unstructured N-terminal region of Aub leading to assembly of the piRNA amplification complex.
Nat Commun, 12, 2021
7CFB
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BU of 7cfb by Molmil
Drosophila melanogaster Krimper eTud1 apo structure
Descriptor: FI20010p1, SULFATE ION
Authors:Hu, H, Li, S.
Deposit date:2020-06-25
Release date:2021-06-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Binding of guide piRNA triggers methylation of the unstructured N-terminal region of Aub leading to assembly of the piRNA amplification complex.
Nat Commun, 12, 2021
6TKZ
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BU of 6tkz by Molmil
Crystal structure of the DHR2 domain of DOCK10 in complex with CDC42
Descriptor: Cell division control protein 42 homolog, Dedicator of cytokinesis protein 10, GLYCEROL, ...
Authors:Barford, D.
Deposit date:2019-11-29
Release date:2020-01-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structural basis for CDC42 and RAC activation by the dual specificity GEF DOCK10
Biorxiv, 2022
1YF5
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BU of 1yf5 by Molmil
Cyto-Epsl: The Cytoplasmic Domain Of Epsl, An Inner Membrane Component Of The Type II Secretion System Of Vibrio Cholerae
Descriptor: General secretion pathway protein L
Authors:Abendroth, J, Murphy, P, Mushtaq, A, Sandkvist, M, Bagdasarian, M, Hol, W.G.
Deposit date:2004-12-30
Release date:2005-05-03
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The X-ray Structure of the Type II Secretion System Complex Formed by the N-terminal Domain of EpsE and the Cytoplasmic Domain of EpsL of Vibrio cholerae.
J.Mol.Biol., 348, 2005
6TKY
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BU of 6tky by Molmil
Crystal structure of the DHR2 domain of DOCK10 in complex with CDC42
Descriptor: Cell division control protein 42 homolog, Dedicator of cytokinesis protein 10, GLYCEROL
Authors:Barford, D, Fan, D, Cronin, N, Yang, J.
Deposit date:2019-11-29
Release date:2020-01-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural basis for CDC42 and RAC activation by the dual specificity GEF DOCK10
Biorxiv, 2022
8I5F
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BU of 8i5f by Molmil
Crystal structure of the DHR-2 domain of DOCK10 in complex with Cdc42 (T17N mutant)
Descriptor: Cell division control protein 42 homolog, Dedicator of cytokinesis protein 10
Authors:Kukimoto-Niino, M, Mishima-Tsumagari, C, Fukui, Y, Yokoyama, S, Shirouzu, M.
Deposit date:2023-01-25
Release date:2023-03-15
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for the dual GTPase specificity of the DOCK10 guanine nucleotide exchange factor.
Biochem.Biophys.Res.Commun., 653, 2023
1KI1
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BU of 1ki1 by Molmil
Guanine Nucleotide Exchange Region of Intersectin in Complex with Cdc42
Descriptor: G25K GTP-binding protein, placental isoform, SULFATE ION, ...
Authors:Snyder, J.T, Pruitt, W.M, Der, C.J, Sondek, J.
Deposit date:2001-12-02
Release date:2002-05-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.
Nat.Struct.Biol., 9, 2002
1KMO
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BU of 1kmo by Molmil
Crystal structure of the Outer Membrane Transporter FecA
Descriptor: HEPTANE-1,2,3-TRIOL, Iron(III) dicitrate transport protein fecA, LAURYL DIMETHYLAMINE-N-OXIDE
Authors:Ferguson, A.D, Chakraborty, R, Smith, B.S, Esser, L, van der Helm, D, Deisenhofer, J.
Deposit date:2001-12-17
Release date:2002-03-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of gating by the outer membrane transporter FecA.
Science, 295, 2002
1KMP
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BU of 1kmp by Molmil
Crystal structure of the Outer Membrane Transporter FecA Complexed with Ferric Citrate
Descriptor: CITRIC ACID, FE (III) ION, IRON(III) DICITRATE TRANSPORT PROTEIN FECA, ...
Authors:Ferguson, A.D, Chakraborty, R, Smith, B.S, Esser, L, van der Helm, D, Deisenhofer, J.
Deposit date:2001-12-17
Release date:2002-03-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of gating by the outer membrane transporter FecA.
Science, 295, 2002
2J6R
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BU of 2j6r by Molmil
FaeG from F4ac ETEC strain GIS26, produced in tobacco plant chloroplast
Descriptor: K88 FIMBRIAL PROTEIN, PHOSPHATE ION
Authors:Van Molle, I, Joensuu, J.J, Buts, L, Panjikar, S, Kotiaho, M, Bouckaert, J, Wyns, L, Niklander-Teeri, V, De Greve, H.
Deposit date:2006-10-03
Release date:2007-04-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Chloroplasts Assemble the Major Subunit Faeg of Escherichia Coli F4 (K88) Fimbriae Into Strand-Swapped Dimers
J.Mol.Biol., 368, 2007
1KCX
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BU of 1kcx by Molmil
X-ray structure of NYSGRC target T-45
Descriptor: DIHYDROPYRIMIDINASE RELATED PROTEIN-1
Authors:Deo, R.C, Schmidt, E.F, Strittmatter, S.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2001-11-11
Release date:2003-08-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Structural bases for CRMP function in plexin-dependent semaphorin3A signaling
Embo J., 23, 2004
3N7Y
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BU of 3n7y by Molmil
Crystal Structure of the Grb2 SH2 Domain in Complex with a 20-Membered Macrocyclic Ligand Having the Sequence pYVNV
Descriptor: 20-membered peptide-like macrocyclic ligand, Growth factor receptor-bound protein 2
Authors:Whiddon, B.B, Clements, J.H, Martin, S.F.
Deposit date:2010-05-27
Release date:2011-01-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Thermodynamic and Structural Effects of Macrocyclization as a Constraining Method in Protein-Ligand Interactions.
ACS MED.CHEM.LETT., 1, 2010
1KZ7
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BU of 1kz7 by Molmil
Crystal Structure of the DH/PH Fragment of Murine Dbs in Complex with the Placental Isoform of Human Cdc42
Descriptor: CDC42 HOMOLOG, GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS
Authors:Rossman, K.L, Worthylake, D.K, Snyder, J.T, Siderovski, D.P, Campbell, S.L, Sondek, J.
Deposit date:2002-02-06
Release date:2002-03-20
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.
EMBO J., 21, 2002
1KZG
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BU of 1kzg by Molmil
DbsCdc42(Y889F)
Descriptor: CDC42 HOMOLOG, GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS
Authors:Rossman, K.L, Worthylake, D.K, Snyder, J.T, Siderovski, D.P, Campbell, S.L, Sondek, J.
Deposit date:2002-02-06
Release date:2002-03-20
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.
EMBO J., 21, 2002
4E9J
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BU of 4e9j by Molmil
Crystal structure of the N-terminal domain of the secretin XcpQ from Pseudomonas aeruginosa
Descriptor: General secretion pathway protein D, MAGNESIUM ION
Authors:Van der Meeren, R.
Deposit date:2012-03-21
Release date:2012-12-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:New Insights into the Assembly of Bacterial Secretins: STRUCTURAL STUDIES OF THE PERIPLASMIC DOMAIN OF XcpQ FROM PSEUDOMONAS AERUGINOSA.
J.Biol.Chem., 288, 2013
4EC5
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BU of 4ec5 by Molmil
Crystal structure of the S210C (dimer) mutant from the N-terminal domain of the secretin XcpQ from Pseudomonas aeruginosa
Descriptor: CALCIUM ION, General secretion pathway protein D
Authors:Van der Meeren, R, Savvides, S.
Deposit date:2012-03-26
Release date:2012-12-05
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.197 Å)
Cite:New Insights into the Assembly of Bacterial Secretins: STRUCTURAL STUDIES OF THE PERIPLASMIC DOMAIN OF XcpQ FROM PSEUDOMONAS AERUGINOSA.
J.Biol.Chem., 288, 2013
5C2J
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BU of 5c2j by Molmil
Complex structure of the GAP domain of MgcRacGAP and Cdc42
Descriptor: ALUMINUM FLUORIDE, Cell division control protein 42 homolog, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Murayama, K, Kato-Murayama, M, Hosaka, T, Kitamura, T, Yokoyama, S, Shirouzu, M.
Deposit date:2015-06-16
Release date:2016-06-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of G-protein target alternation of MgcRacGAP by phospholylation
To Be Published
5CJP
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BU of 5cjp by Molmil
The Structural Basis for Cdc42-Induced Dimerization of IQGAPs
Descriptor: Cell division cycle 42 (GTP binding protein, 25kDa), isoform CRA_a, ...
Authors:Worthylake, D.K, Boyapati, V.K, LeCour Jr, L.
Deposit date:2015-07-14
Release date:2016-08-10
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Structural Basis for Cdc42-Induced Dimerization of IQGAPs.
Structure, 24, 2016
4YC7
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BU of 4yc7 by Molmil
Crystal structure of human FMNL2 GBD-FH3 Domains bound to Cdc42-GppNHp
Descriptor: Cell division control protein 42 homolog, Formin-like protein 2, MAGNESIUM ION, ...
Authors:Kuhn, S, Geyer, M.
Deposit date:2015-02-19
Release date:2015-05-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structure of FMNL2-Cdc42 yields insights into the mechanism of lamellipodia and filopodia formation.
Nat Commun, 6, 2015
5FI1
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BU of 5fi1 by Molmil
Crystal Structure of the P-Rex1 DH/PH tandem in complex with Cdc42
Descriptor: Cell division control protein 42 homolog, Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein,Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
Authors:Cash, J.N, Tesmer, J.J.G.
Deposit date:2015-12-22
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.203 Å)
Cite:Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3.
Structure, 24, 2016
3QBV
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BU of 3qbv by Molmil
Structure of designed orthogonal interaction between CDC42 and nucleotide exchange domains of intersectin
Descriptor: Cell division control protein 42 homolog, GUANOSINE-5'-DIPHOSPHATE, Intersectin-1
Authors:Kapp, G.T, Remenyi, A, Lim, W.A, Kortemme, T.
Deposit date:2011-01-14
Release date:2012-02-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Control of protein signaling using a computationally designed GTPase/GEF orthogonal pair.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VHL
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BU of 3vhl by Molmil
Crystal structure of the DHR-2 domain of DOCK8 in complex with Cdc42 (T17N mutant)
Descriptor: Cell division control protein 42 homolog, Dedicator of cytokinesis protein 8, PHOSPHATE ION
Authors:Hanawa-Suetsugu, K, Kukimoto-Niino, M, Nishizak, T, Terada, T, Shirouzu, M, Fukui, Y, Yokoyama, S.
Deposit date:2011-08-26
Release date:2012-06-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.085 Å)
Cite:DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses.
Blood, 119, 2012

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PDB entries from 2024-08-07

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