8I5F
Crystal structure of the DHR-2 domain of DOCK10 in complex with Cdc42 (T17N mutant)
Summary for 8I5F
| Entry DOI | 10.2210/pdb8i5f/pdb |
| Related | 8I5V 8I5W |
| Descriptor | Dedicator of cytokinesis protein 10, Cell division control protein 42 homolog (3 entities in total) |
| Functional Keywords | gef, gtpase, rho, cdc42, rac, signaling protein |
| Biological source | Mus musculus (house mouse) More |
| Total number of polymer chains | 4 |
| Total formula weight | 156928.79 |
| Authors | Kukimoto-Niino, M.,Mishima-Tsumagari, C.,Fukui, Y.,Yokoyama, S.,Shirouzu, M. (deposition date: 2023-01-25, release date: 2023-03-15) |
| Primary citation | Kukimoto-Niino, M.,Ihara, K.,Mishima-Tsumagari, C.,Inoue, M.,Fukui, Y.,Yokoyama, S.,Shirouzu, M. Structural basis for the dual GTPase specificity of the DOCK10 guanine nucleotide exchange factor. Biochem.Biophys.Res.Commun., 653:12-20, 2023 Cited by PubMed: 36848820DOI: 10.1016/j.bbrc.2023.02.054 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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