6TKY
Crystal structure of the DHR2 domain of DOCK10 in complex with CDC42
Summary for 6TKY
| Entry DOI | 10.2210/pdb6tky/pdb |
| Descriptor | Dedicator of cytokinesis protein 10, Cell division control protein 42 homolog, GLYCEROL, ... (5 entities in total) |
| Functional Keywords | dock10 gef cdc42 gtpase, signaling protein |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 148302.43 |
| Authors | Barford, D.,Fan, D.,Cronin, N.,Yang, J. (deposition date: 2019-11-29, release date: 2020-01-22, Last modification date: 2024-01-24) |
| Primary citation | Fan, D.,Yang, J.,Cronin, N.,Barford, D. Structural basis for CDC42 and RAC activation by the dual specificity GEF DOCK10 Biorxiv, 2022 Cited by DOI: 10.1101/2022.06.15.496229PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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