6TKZ
Crystal structure of the DHR2 domain of DOCK10 in complex with CDC42
This is a non-PDB format compatible entry.
Summary for 6TKZ
Entry DOI | 10.2210/pdb6tkz/pdb |
Related | 6TKY |
Descriptor | Dedicator of cytokinesis protein 10, Cell division control protein 42 homolog, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | guanine nucleotide exchange factor, cytoskeleton, actin, cryoem, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 149061.70 |
Authors | Barford, D. (deposition date: 2019-11-29, release date: 2020-01-22, Last modification date: 2024-01-31) |
Primary citation | Fan, D.,Yang, J.,Cronin, N.,Barford, D. Structural basis for CDC42 and RAC activation by the dual specificity GEF DOCK10 Biorxiv, 2022 Cited by DOI: 10.1101/2022.06.15.496229PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.64 Å) |
Structure validation
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