6TKZ

Crystal structure of the DHR2 domain of DOCK10 in complex with CDC42

This is a non-PDB format compatible entry.

Summary for 6TKZ

• Entry DOI: 10.2210/pdb6tkz/pdb
• Related: 6TKY
• Descriptor: Dedicator of cytokinesis protein 10, Cell division control protein 42 homolog, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: guanine nucleotide exchange factor, cytoskeleton, actin, cryoem, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 149061.70

Authors

Barford, D. (deposition date: 2019-11-29, release date: 2020-01-22, Last modification date: 2024-01-31)

• Primary citation: Fan, D.,Yang, J.,Cronin, N.,Barford, D.; Structural basis for CDC42 and RAC activation by the dual specificity GEF DOCK10; Biorxiv, 2022; DOI: 10.1101/2022.06.15.496229

Experimental method

X-RAY DIFFRACTION (2.64 Å)