Guanine Nucleotide Exchange Region of Intersectin in Complex with Cdc42

Summary for 1KI1

DescriptorG25K GTP-binding protein, placental isoform, intersectin long form, SULFATE ION, ... (4 entities in total)
Functional Keywordsprotein-protein complex, dh domain, ph domain, rho gtpase, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationCell membrane; Lipid-anchor; Cytoplasmic side (Potential) P60953
Endomembrane system (By similarity) Q15811
Total number of polymer chains4
Total molecular weight123949.31
Snyder, J.T.,Pruitt, W.M.,Der, C.J.,Sondek, J. (deposition date: 2001-12-02, release date: 2002-05-29, Last modification date: 2011-07-13)
Primary citation
Snyder, J.T.,Worthylake, D.K.,Rossman, K.L.,Betts, L.,Pruitt, W.M.,Siderovski, D.P.,Der, C.J.,Sondek, J.
Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.
Nat.Struct.Biol., 9:468-475, 2002
PubMed: 12006984 (PDB entries with the same primary citation)
DOI: 10.1038/nsb796
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers243.7%5.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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