PDB: 9904 resultsInfo pagesStatus searchChemie searchBIRD

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8YTN	Single-chain Fv antibody of E11 Descriptor: GLYCEROL, Single-chain Fv antibody of E11 Authors: Yoshida, M, Hanazono, Y, Numoto, N, Ito, N, Oda, M. Deposit date: 2024-03-26 Release date: 2024-07-03 Last modified: 2024-07-10 Method: X-RAY DIFFRACTION (1.72 Å) Cite: Affinity-matured antibody with a disulfide bond in H-CDR3 loop. Arch.Biochem.Biophys., 758, 2024
7UEM	Genomic and structural basis for the human anti-alpha-galactosyl antibody response Descriptor: CHLORIDE ION, Heavy chain Fab arm of antibody HKB7, Light chain Fab of antibody HKB7, ... Authors: Langley, D.B, Christ, D. Deposit date: 2022-03-22 Release date: 2022-06-29 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.314 Å) Cite: Genetic and structural basis of the human anti-alpha-galactosyl antibody response. Proc.Natl.Acad.Sci.USA, 119, 2022
7UEL	Genetic and structural basis for the human anti-alpha-galactosyl antibody response Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Heavy chain Fab of antibody JEC1, ... Authors: Langley, D.B, Christ, D. Deposit date: 2022-03-22 Release date: 2022-06-29 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Genetic and structural basis of the human anti-alpha-galactosyl antibody response. Proc.Natl.Acad.Sci.USA, 119, 2022
7UEN	Genetic and structural basis of the human anti-alpha-galactosyl antibody response Descriptor: M86 antibody Fab heavy chain, M86 antibody Fab light chain, PHOSPHATE ION, ... Authors: Langley, D.B, Christ, D. Deposit date: 2022-03-22 Release date: 2022-06-29 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Genetic and structural basis of the human anti-alpha-galactosyl antibody response. Proc.Natl.Acad.Sci.USA, 119, 2022
7U0D	Local refinement of cryo-EM structure of the interface of the Omicron RBD in complex with antibodies B-182.1 and A19-46.1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SARS-CoV-2 antibody A19-46.1, Heavy chain of SARS-CoV-2 antibody B1-182.1, ... Authors: Zhou, T, kwong, P.D. Deposit date: 2022-02-17 Release date: 2022-03-30 Last modified: 2022-10-19 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529. Science, 376, 2022
5TIH	Structural basis for inhibition of erythrocyte invasion by antibodies to Plasmodium falciparum protein CyRPA Descriptor: ACETATE ION, CyRPA antibody Fab Heavy Chain, CyRPA antibody Fab Light Chain, ... Authors: Chen, L, Xu, Y, Wang, W, Thompson, J.K, Goddard-Borger, E, Lawrence, M.C, Cowman, A.F. Deposit date: 2016-10-03 Release date: 2017-03-01 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.44 Å) Cite: Structural basis for inhibition of erythrocyte invasion by antibodies toPlasmodium falciparumprotein CyRPA. Elife, 6, 2017
7TCA	Cryo-EM structure of SARS-CoV-2 Omicron spike in complex with antibody A19-46.1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of antibody A19-46.1, ... Authors: Zhou, T, Kwong, P.D. Deposit date: 2021-12-23 Release date: 2022-03-30 Last modified: 2022-10-19 Method: ELECTRON MICROSCOPY (3.85 Å) Cite: Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529. Science, 376, 2022
7TC9	Locally refined region of SARS-CoV-2 spike in complex with antibody A19-46.1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of antibody A19-46.1, Light chain of antibody A19-46.1, ... Authors: Zhou, T, Kwong, P.D. Deposit date: 2021-12-23 Release date: 2022-03-30 Last modified: 2022-10-19 Method: ELECTRON MICROSCOPY (5.08 Å) Cite: Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529. Science, 376, 2022
6VJT	Co-crystals of broadly neutralizing antibody with the linear epitope from Hepatitis B surface antigen Descriptor: Heavy Chain Fab Fragment of Monoclonal Ab15, Light Chain Fab Fragment of Monoclonal antibody A15, antigenic region 139-148 of Hepatitis B surface antigen protein Authors: Oren, D.A, Nussenzweig, M.C, Wang, Q. Deposit date: 2020-01-17 Release date: 2020-08-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.782 Å) Cite: A Combination of Human Broadly Neutralizing Antibodies against Hepatitis B Virus HBsAg with Distinct Epitopes Suppresses Escape Mutations. Cell Host Microbe, 28, 2020
6NF2	Cryo-EM structure of vaccine-elicited antibody 0PV-c.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122 Descriptor: 0PV-c.01 Heavy Chain, 0PV-c.01 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Gorman, J, Kwong, P.D. Deposit date: 2018-12-18 Release date: 2019-07-24 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019
7KFW	Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-B3 Fab) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, heavy chain of antibody C1A-B3 Fab, ... Authors: Pan, J, Abraham, J, Clark, L, Clark, S. Deposit date: 2020-10-15 Release date: 2020-12-02 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.792 Å) Cite: Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2. Biorxiv, 2020
8SMT	Crystal structure of antibody WRAIR-2134 in complex with SARS-CoV-2 receptor binding domain Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, WRAIR-2134 Fab heavy chain, ... Authors: Sankhala, R.S, Jensen, J.L, Joyce, M.G. Deposit date: 2023-04-26 Release date: 2023-06-28 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (3.16 Å) Cite: Antibody targeting of conserved sites of vulnerability on the SARS-CoV-2 spike receptor-binding domain. Structure, 32, 2024
7TCQ	Crystal structure of SARS-CoV-2 neutralizing antibody WS6 in complex with spike S2 peptide Descriptor: Anti-SARS-CoV-2 antibody WS6 Fab heavy chain, Anti-SARS-CoV-2 antibody WS6 Fab light chain, DI(HYDROXYETHYL)ETHER, ... Authors: Zhou, T, Kwong, P.D. Deposit date: 2021-12-28 Release date: 2022-08-03 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability. Structure, 30, 2022
8SMI	Crystal structure of antibody WRAIR-2123 in complex with SARS-CoV-2 receptor binding domain Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, WRAIR-2123 Fab heavy chain, ... Authors: Sankhala, R.S, Jensen, J.L, Joyce, M.G. Deposit date: 2023-04-26 Release date: 2023-12-13 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Antibody targeting of conserved sites of vulnerability on the SARS-CoV-2 spike receptor-binding domain. Structure, 32, 2024
3UTZ	Endogenous-like inhibitory antibodies targeting activated metalloproteinase motifs show therapeutic potential Descriptor: Metalloproteinase, heavy chain, light chain, ... Authors: Sela-Passwell, N, Kikkeri, R, Dym, O, Rozenberg, H, Margalit, R, Arad-Yellin, R, Eisenstein, M, Brenner, O, Shoham, T, Danon, T, Shanzer, A, Sagi, I, Israel Structural Proteomics Center (ISPC) Deposit date: 2011-11-27 Release date: 2011-12-14 Last modified: 2017-03-15 Method: X-RAY DIFFRACTION (2.18 Å) Cite: Antibodies targeting the catalytic zinc complex of activated matrix metalloproteinases show therapeutic potential. NAT.MED. (N.Y.), 18, 2012
7KFV	Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-B12 Fab) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of antibody C1A-B12 Fab, Spike glycoprotein, ... Authors: Pan, J, Abraham, J, Clark, L, Clark, S. Deposit date: 2020-10-15 Release date: 2020-12-02 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.102 Å) Cite: Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2. Biorxiv, 2020
7KFY	Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-F10 Fab) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, heavy chain of human antibody C1A-F10 Fab, ... Authors: Pan, J, Abraham, J, Clark, L, Clark, S. Deposit date: 2020-10-15 Release date: 2020-12-02 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.157 Å) Cite: Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2. Biorxiv, 2020
7KFX	Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-C2 Fab) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, heavy chain of human antibody C1A-C2 Fab, ... Authors: Pan, J, Abraham, J, Clark, L, Clark, S. Deposit date: 2020-10-15 Release date: 2020-12-02 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.226 Å) Cite: Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2. Biorxiv, 2020
7TFN	Cryo-EM structure of CD4bs antibody Ab1303 in complex with HIV-1 Env trimer BG505 SOSIP.664 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-HIV-1 CD4bs antibody Fab Ab1303 - Heavy chain, ... Authors: Yang, Z, Bjorkman, P.J. Deposit date: 2022-01-06 Release date: 2022-01-19 Last modified: 2022-02-23 Method: ELECTRON MICROSCOPY (4 Å) Cite: Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer. Nat Commun, 13, 2022
7TFO	Cryo-EM structure of HIV-1 Env trimer BG505 SOSIP.664 in complex with CD4bs antibody Ab1573 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD4 binding site antibody Ab1573 - Fab heavy chain, ... Authors: Yang, Z, Bjorkman, P.J. Deposit date: 2022-01-06 Release date: 2022-01-26 Last modified: 2022-02-23 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer. Nat Commun, 13, 2022
8FAH	Crystal structure of SARS-CoV-2 receptor binding domain in complex with SARS-CoV-2 reactive human antibody CR3022 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR3022 Fab heavy chain, CR3022 Fab light chain, ... Authors: Sankhala, R.S, Jensen, J.L, Joyce, M.G. Deposit date: 2022-11-26 Release date: 2023-12-13 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (4.22 Å) Cite: Antibody targeting of conserved sites of vulnerability on the SARS-CoV-2 spike receptor-binding domain. Structure, 32, 2024
7LRT	Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody A23-58.1 that targets the receptor-binding domain Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SARS-CoV-2 spike glycoprotein, ... Authors: Zhou, T, Tsybovsky, T. Deposit date: 2021-02-17 Release date: 2021-07-14 Last modified: 2021-08-25 Method: ELECTRON MICROSCOPY (3.54 Å) Cite: Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants. Science, 373, 2021
7MDT	BG505 SOSIP.v5.2 in complex with the monoclonal antibody Rh4O9.8 (as Fab fragment) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Rh4O9.8 monoclonal antibody Heavy Chain, ... Authors: Antanasijevic, A, Ozorowski, G, Nogal, B, Ward, A.B. Deposit date: 2021-04-06 Release date: 2022-01-26 Last modified: 2022-02-02 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: From structure to sequence: Antibody discovery using cryoEM. Sci Adv, 8, 2022
7X6O	Cryo-EM structure of H1 hemagglutinin from A/Washington/05/2011 in complex with a neutralizing antibody 28-12 Descriptor: Heavy chain of antibody 12 fab, Hemagglutinin, The light chain of antibody 12 fab Authors: Cong, Y, Liu, C.X. Deposit date: 2022-03-07 Release date: 2022-03-23 Last modified: 2022-06-22 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Unique binding pattern for a lineage of human antibodies with broad reactivity against influenza A virus. Nat Commun, 13, 2022
7X28	MERS-CoV spike complex with S41 neutralizing antibody Fab Class3 (2u1d RBD with 2Fab) Descriptor: Spike glycoprotein, antibody S41 heavy chain, antibody S41 light chain Authors: Zeng, J.W, Zhang, S.Y, Zhou, H.X, Wang, X.W. Deposit date: 2022-02-25 Release date: 2023-01-18 Last modified: 2023-01-25 Method: ELECTRON MICROSCOPY (2.49 Å) Cite: Cryoelectron microscopy structures of a human neutralizing antibody bound to MERS-CoV spike glycoprotein. Front Microbiol, 13, 2022

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