7KFV
Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-B12 Fab)
Summary for 7KFV
Entry DOI | 10.2210/pdb7kfv/pdb |
Related | 7KFW 7KFX 7KFY |
Descriptor | Spike glycoprotein, Heavy chain of antibody C1A-B12 Fab, light chain of antibody C1A-B3 Fab, ... (5 entities in total) |
Functional Keywords | covid-19, sars-cov-2, neutralizing antibody, affinity maturation, immune system, immune system-viral protein complex, immune system/viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 9 |
Total formula weight | 218196.80 |
Authors | Pan, J.,Abraham, J.,Clark, L.,Clark, S. (deposition date: 2020-10-15, release date: 2020-12-02, Last modification date: 2023-10-18) |
Primary citation | Clark, S.A.,Clark, L.E.,Pan, J.,Coscia, A.,McKay, L.G.A.,Shankar, S.,Johnson, R.I.,Griffiths, A.,Abraham, J. Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2. Biorxiv, 2020 Cited by PubMed: 33200128DOI: 10.1101/2020.11.13.381533 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.102 Å) |
Structure validation
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