7UEL

Genetic and structural basis for the human anti-alpha-galactosyl antibody response

Replaces:  6NUZ

Summary for 7UEL

• Entry DOI: 10.2210/pdb7uel/pdb
• Descriptor: Heavy chain Fab of antibody JEC1, Light chain Fab of antibody JEC1, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: alpha-galactosyl, antibody, anti-alpha-gal, immune response, m86, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 47622.59

Authors

Langley, D.B.,Christ, D. (deposition date: 2022-03-22, release date: 2022-06-29, Last modification date: 2024-04-03)

• Primary citation: Langley, D.B.,Schofield, P.,Nevoltris, D.,Jackson, J.,Jackson, K.J.L.,Peters, T.J.,Burk, M.,Matthews, J.M.,Basten, A.,Goodnow, C.C.,van Nunen, S.,Reed, J.H.,Christ, D.; Genetic and structural basis of the human anti-alpha-galactosyl antibody response.; Proc.Natl.Acad.Sci.USA, 119:e2123212119-e2123212119, 2022; PubMed: 35867757; DOI: 10.1073/pnas.2123212119

Experimental method

X-RAY DIFFRACTION (1.9 Å)