7KFY
Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-F10 Fab)
Summary for 7KFY
| Entry DOI | 10.2210/pdb7kfy/pdb |
| Related | 7KFV 7KFW 7KFX |
| Descriptor | Spike glycoprotein, heavy chain of human antibody C1A-F10 Fab, light chain of human antibody C1A-F10 Fab, ... (5 entities in total) |
| Functional Keywords | covid-19, sars-cov-2, neutralizing antibody, affinity maturation, immune system, immune system-viral protein complex, immune system/viral protein |
| Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
| Total number of polymer chains | 3 |
| Total formula weight | 72791.25 |
| Authors | Pan, J.,Abraham, J.,Clark, L.,Clark, S. (deposition date: 2020-10-15, release date: 2020-12-02, Last modification date: 2023-10-18) |
| Primary citation | Clark, S.A.,Clark, L.E.,Pan, J.,Coscia, A.,McKay, L.G.A.,Shankar, S.,Johnson, R.I.,Griffiths, A.,Abraham, J. Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2. Biorxiv, 2020 Cited by PubMed: 33200128DOI: 10.1101/2020.11.13.381533 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.157 Å) |
Structure validation
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