7TFN

Cryo-EM structure of CD4bs antibody Ab1303 in complex with HIV-1 Env trimer BG505 SOSIP.664

Summary for 7TFN

Entry DOI	10.2210/pdb7tfn/pdb
EMDB information	25877
Descriptor	Envelope glycoprotein BG505 SOSIP.664 - gp120, 2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose, ... (11 entities in total)
Functional Keywords	hiv-1 env, neutralizing antibody, cd4 binding site antibody, viral protein, viral protein-immune system complex, viral protein/immune system
Biological source	Human immunodeficiency virus 1 More
Total number of polymer chains	12
Total formula weight	371403.56
Authors	Yang, Z.,Bjorkman, P.J. (deposition date: 2022-01-06, release date: 2022-01-19, Last modification date: 2022-02-23)
Primary citation	Yang, Z.,Dam, K.A.,Bridges, M.D.,Hoffmann, M.A.G.,DeLaitsch, A.T.,Gristick, H.B.,Escolano, A.,Gautam, R.,Martin, M.A.,Nussenzweig, M.C.,Hubbell, W.L.,Bjorkman, P.J. Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer. Nat Commun, 13:732-732, 2022 Cited by PubMed: 35136084 DOI: 10.1038/s41467-022-28424-3 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4 Å)

Structure validation