3UTZ
Endogenous-like inhibitory antibodies targeting activated metalloproteinase motifs show therapeutic potential
Summary for 3UTZ
Entry DOI | 10.2210/pdb3utz/pdb |
Descriptor | Metalloproteinase, light chain, Metalloproteinase, heavy chain, SULFATE ION, ... (4 entities in total) |
Functional Keywords | structural genomics, israel structural proteomics center, ispc, fab domain, immune system |
Biological source | Mus musculus (mouse) More |
Total number of polymer chains | 6 |
Total formula weight | 145452.28 |
Authors | Sela-Passwell, N.,Kikkeri, R.,Dym, O.,Rozenberg, H.,Margalit, R.,Arad-Yellin, R.,Eisenstein, M.,Brenner, O.,Shoham, T.,Danon, T.,Shanzer, A.,Sagi, I.,Israel Structural Proteomics Center (ISPC) (deposition date: 2011-11-27, release date: 2011-12-14, Last modification date: 2017-03-15) |
Primary citation | Sela-Passwell, N.,Kikkeri, R.,Dym, O.,Rozenberg, H.,Margalit, R.,Arad-Yellin, R.,Eisenstein, M.,Brenner, O.,Shoham, T.,Danon, T.,Shanzer, A.,Sagi, I. Antibodies targeting the catalytic zinc complex of activated matrix metalloproteinases show therapeutic potential. NAT.MED. (N.Y.), 18:143-147, 2012 Cited by PubMed: 22198278DOI: 10.1038/nm.2582 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.18 Å) |
Structure validation
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