7TCA

Cryo-EM structure of SARS-CoV-2 Omicron spike in complex with antibody A19-46.1

Summary for 7TCA

• Entry DOI: 10.2210/pdb7tca/pdb
• EMDB information: 25807
• Descriptor: Spike glycoprotein, Heavy chain of antibody A19-46.1, Light chain of antibody A19-46.1, ... (5 entities in total)
• Functional Keywords: sars-cov-2, spike, antibody, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 7
• Total formula weight: 530729.49

Authors

Zhou, T.,Kwong, P.D. (deposition date: 2021-12-23, release date: 2022-03-30, Last modification date: 2022-10-19)

• Primary citation: Zhou, T.,Wang, L.,Misasi, J.,Pegu, A.,Zhang, Y.,Harris, D.R.,Olia, A.S.,Talana, C.A.,Yang, E.S.,Chen, M.,Choe, M.,Shi, W.,Teng, I.T.,Creanga, A.,Jenkins, C.,Leung, K.,Liu, T.,Stancofski, E.D.,Stephens, T.,Zhang, B.,Tsybovsky, Y.,Graham, B.S.,Mascola, J.R.,Sullivan, N.J.,Kwong, P.D.; Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529.; Science, 376:eabn8897-eabn8897, 2022; PubMed: 35324257; DOI: 10.1126/science.abn8897

Experimental method

ELECTRON MICROSCOPY (3.85 Å)