Structural basis for inhibition of erythrocyte invasion by antibodies to Plasmodium falciparum protein CyRPA

Summary for 5TIH

DescriptorCysteine-rich protective antigen, CyRPA antibody Fab Heavy Chain, CyRPA antibody Fab Light Chain, ... (5 entities in total)
Functional Keywordsplasmodium falciparum cyrpa inhibitory antibody, immune system
Biological sourcePlasmodium falciparum
Total number of polymer chains3
Total molecular weight86538.62
Chen, L.,Xu, Y.,Wang, W.,Thompson, J.K.,Goddard-Borger, E.,Lawrence, M.C.,Cowman, A.F. (deposition date: 2016-10-03, release date: 2017-03-01, Last modification date: 2020-01-08)
Primary citation
Chen, L.,Xu, Y.,Wong, W.,Thompson, J.K.,Healer, J.,Goddard-Borger, E.D.,Lawrence, M.C.,Cowman, A.F.
Structural basis for inhibition of erythrocyte invasion by antibodies toPlasmodium falciparumprotein CyRPA.
Elife, 6:-, 2017
PubMed: 28195530 (PDB entries with the same primary citation)
DOI: 10.7554/eLife.21347
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.211300.4%1.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload