3LDB
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![BU of 3ldb by Molmil](/molmil-images/mine/3ldb) | Structure of JMJD6 complexd with ALPHA-KETOGLUTARATE and Fab Fragment. | Descriptor: | 2-OXOGLUTARIC ACID, Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, FE (III) ION, ... | Authors: | Hong, X, Zang, J, White, J, Kappler, J.W, Wang, C, Zhang, G. | Deposit date: | 2010-01-12 | Release date: | 2010-08-04 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Interaction of JMJD6 with single-stranded RNA. Proc.Natl.Acad.Sci.USA, 107, 2010
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3NIG
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![BU of 3nig by Molmil](/molmil-images/mine/3nig) | The Closed Headpiece of Integrin IIb 3 and its Complex with an IIb 3 -Specific Antagonist That Does Not Induce Opening | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Zhu, J.H, Zhu, J.Q, Springer, T.A. | Deposit date: | 2010-06-15 | Release date: | 2010-12-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Closed headpiece of integrin {alpha}IIb{beta}3 and its complex with an {alpha}IIb{beta}3-specific antagonist that does not induce opening. Blood, 116, 2010
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3NIF
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![BU of 3nif by Molmil](/molmil-images/mine/3nif) | The Closed Headpiece of Integrin IIb 3 and its Complex with an IIb 3 -Specific Antagonist That Does Not Induce Opening | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-ethyl-7-piperazin-1-yl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one, ... | Authors: | Zhu, J.H, Zhu, J.Q, Springer, T.A. | Deposit date: | 2010-06-15 | Release date: | 2010-12-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Closed headpiece of integrin {alpha}IIb{beta}3 and its complex with an {alpha}IIb{beta}3-specific antagonist that does not induce opening. Blood, 116, 2010
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6WLA
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![BU of 6wla by Molmil](/molmil-images/mine/6wla) | Antigen binding fragment of ch128.1 | Descriptor: | Fab ch128.1 heavy chain, Fab ch128.1 light chain, GLYCEROL | Authors: | Helguera, G, Rodriguez, J.A, Sawaya, M, Cascio, D, Zink, S, Ziegenbein, J, Short, C. | Deposit date: | 2020-04-18 | Release date: | 2021-03-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Host receptor-targeted therapeutic approach to counter pathogenic New World mammarenavirus infections. Nat Commun, 13, 2022
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3C09
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![BU of 3c09 by Molmil](/molmil-images/mine/3c09) | Crystal structure the Fab fragment of matuzumab (Fab72000) in complex with domain III of the extracellular region of EGFR | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, Matuzumab Fab Heavy chain, ... | Authors: | Ferguson, K.M, Schmiedel, J, Knoechel, T. | Deposit date: | 2008-01-18 | Release date: | 2008-04-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Matuzumab binding to EGFR prevents the conformational rearrangement required for dimerization. Cancer Cell, 13, 2008
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1KYO
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![BU of 1kyo by Molmil](/molmil-images/mine/1kyo) | |
1MCO
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![BU of 1mco by Molmil](/molmil-images/mine/1mco) | THREE-DIMENSIONAL STRUCTURE OF A HUMAN IMMUNOGLOBULIN WITH A HINGE DELETION | Descriptor: | IGG1 MCG INTACT ANTIBODY (HEAVY CHAIN), IGG1 MCG INTACT ANTIBODY (LIGHT CHAIN), N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-L-gulopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Guddat, L.W, Edmundson, A.B. | Deposit date: | 1993-02-25 | Release date: | 1994-01-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Three-dimensional structure of a human immunoglobulin with a hinge deletion. Proc.Natl.Acad.Sci.Usa, 90, 1993
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1N5Y
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![BU of 1n5y by Molmil](/molmil-images/mine/1n5y) | HIV-1 Reverse Transcriptase Crosslinked to Post-Translocation AZTMP-Terminated DNA (Complex P) | Descriptor: | 5'-D(*A*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*(ATM))-3', 5'-D(*AP*TP*GP*C*TP*AP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*GP*TP*G)-3', MAGNESIUM ION, ... | Authors: | Sarafianos, S.G, Clark Jr, A.D, Das, K, Tuske, S, Birktoft, J.J, Ilankumaran, P, Ramesha, A.R, Sayer, J.M, Jerina, D.M, Boyer, P.L, Hughes, S.H, Arnold, E. | Deposit date: | 2002-11-07 | Release date: | 2003-01-28 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of HIV-1 Reverse Transcriptase with Pre-Translocation and Post-Translocation AZTMP-Terminated DNA Embo J., 21, 2002
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1N6Q
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![BU of 1n6q by Molmil](/molmil-images/mine/1n6q) | HIV-1 Reverse Transcriptase Crosslinked to pre-translocation AZTMP-terminated DNA (complex N) | Descriptor: | 5'-D(*A*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*AP*(ATM))-3', 5'-D(*AP*T*GP*CP*AP*TP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*GP*TP*G)-3', MAGNESIUM ION, ... | Authors: | Sarafianos, S.G, Clark Jr, A.D, Das, K, Tuske, S, Birktoft, J.J, Ilankumaran, I, Ramesha, A.R, Sayer, J.M, Jerina, D.M, Boyer, P.L, Hughes, S.H, Arnold, E. | Deposit date: | 2002-11-11 | Release date: | 2003-01-14 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structures of HIV-1 Reverse Transcriptase with Pre- and Post-translocation AZTMP-terminated DNA Embo J., 21, 2002
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6M38
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![BU of 6m38 by Molmil](/molmil-images/mine/6m38) | X-ray structure of a Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) in S-duloxetine bound form | Descriptor: | (3S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine, Antibody fragment 9D5 heavy chain, Antibody fragment 9D5 light chain, ... | Authors: | Shabareesh, P, Mallela, A.K, Joseph, D, Penmatsa, A. | Deposit date: | 2020-03-02 | Release date: | 2021-02-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.001 Å) | Cite: | Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters. Nat Commun, 12, 2021
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6M3Z
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![BU of 6m3z by Molmil](/molmil-images/mine/6m3z) | X-ray structure of a Drosophila dopamine transporter with NET-like mutations (D121G/S426M/F471L) in milnacipran bound form | Descriptor: | (1R,2S)-2-(aminomethyl)-N,N-diethyl-1-phenyl-cyclopropane-1-carboxamide, Antibody fragment 9D5 Light chain, Antibody fragment 9D5 heavy chain, ... | Authors: | Shabareesh, P, Mallela, A.K, Joseph, D, Penmatsa, A. | Deposit date: | 2020-03-04 | Release date: | 2021-02-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.11 Å) | Cite: | Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters. Nat Commun, 12, 2021
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6M47
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![BU of 6m47 by Molmil](/molmil-images/mine/6m47) | X-ray structure of a Drosophila dopamine transporter with NET-like mutations (D121G/S426M/F471L) in tramadol bound form | Descriptor: | (1S,2S)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexan-1-ol, Antibody fragment 9D5 light chain, Antibody fragment Heavy chain, ... | Authors: | Shabareesh, P, Mallela, A.K, Joseph, D, Penmatsa, A. | Deposit date: | 2020-03-05 | Release date: | 2021-02-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.252 Å) | Cite: | Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters. Nat Commun, 12, 2021
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3QWO
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![BU of 3qwo by Molmil](/molmil-images/mine/3qwo) | |
3FB5
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![BU of 3fb5 by Molmil](/molmil-images/mine/3fb5) | KcsA potassium channel in the partially open state with 14.5 A opening at T112 | Descriptor: | POTASSIUM ION, Voltage-gated potassium channel, antibody Fab fragment heavy chain, ... | Authors: | Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E. | Deposit date: | 2008-11-18 | Release date: | 2010-05-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | KcsA potassium channel in the partially open state with 14.5 A opening at T112 TO BE PUBLISHED
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3FB6
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![BU of 3fb6 by Molmil](/molmil-images/mine/3fb6) | KcsA Potassium channel in the partially open state with 16 A opening at T112 | Descriptor: | POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ... | Authors: | Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E. | Deposit date: | 2008-11-18 | Release date: | 2010-05-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | KcsA Potassium channel in the partially open state with 16 A opening at T112 TO BE PUBLISHED
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3F7Y
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![BU of 3f7y by Molmil](/molmil-images/mine/3f7y) | KcsA Potassium channel in the partially open state with 17 A opening at T112 | Descriptor: | POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ... | Authors: | Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E. | Deposit date: | 2008-11-10 | Release date: | 2010-05-19 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | KcsA Potassium channel in the partially open state with 17 A opening at T112 TO BE PUBLISHED
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3STB
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![BU of 3stb by Molmil](/molmil-images/mine/3stb) | A complex of two editosome proteins and two nanobodies | Descriptor: | MP18 RNA editing complex protein, RNA-editing complex protein MP42, single domain antibody VHH | Authors: | Park, Y.-J, Hol, W. | Deposit date: | 2011-07-09 | Release date: | 2011-11-02 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of a heterodimer of editosome interaction proteins in complex with two copies of a cross-reacting nanobody. Nucleic Acids Res., 40, 2012
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4YBQ
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![BU of 4ybq by Molmil](/molmil-images/mine/4ybq) | Rat GLUT5 with Fv in the outward-open form | Descriptor: | Solute carrier family 2, facilitated glucose transporter member 5, antibody Fv fragment heavy chain, ... | Authors: | Nomura, N, Shimamura, T, Iwata, S. | Deposit date: | 2015-02-19 | Release date: | 2015-10-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.27 Å) | Cite: | Structure and mechanism of the mammalian fructose transporter GLUT5 Nature, 526, 2015
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3HMW
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![BU of 3hmw by Molmil](/molmil-images/mine/3hmw) | Crystal structure of ustekinumab FAB | Descriptor: | CADMIUM ION, USTEKINUMAB FAB HEAVY CHAIN, USTEKINUMAB FAB LIGHT CHAIN | Authors: | Luo, J. | Deposit date: | 2009-05-29 | Release date: | 2010-06-09 | Last modified: | 2015-07-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for the dual recognition of IL-12 and IL-23 by ustekinumab. J.Mol.Biol., 402, 2010
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4B50
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![BU of 4b50 by Molmil](/molmil-images/mine/4b50) | |
3GB7
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![BU of 3gb7 by Molmil](/molmil-images/mine/3gb7) | Potassium Channel KcsA-Fab complex in Li+ | Descriptor: | DIACYL GLYCEROL, NICKEL (II) ION, Voltage-gated potassium channel, ... | Authors: | Thompson, A.N, Ilsoo, K, Panosian, T.D, Iverson, T.M, Allen, T.W, Nimigean, C.M. | Deposit date: | 2009-02-18 | Release date: | 2009-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Mechanism of potassium-channel selectivity revealed by Na(+) and Li(+) binding sites within the KcsA pore. Nat.Struct.Mol.Biol., 16, 2009
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3V4V
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![BU of 3v4v by Molmil](/molmil-images/mine/3v4v) | crystal structure of a4b7 headpiece complexed with Fab ACT-1 and RO0505376 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Yu, Y, Zhu, J, Springer, T.A. | Deposit date: | 2011-12-15 | Release date: | 2012-01-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural specializations of a4b7, an Integrin that Mediates Rolling Adhesion J.Cell Biol., 196, 2012
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3V4P
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![BU of 3v4p by Molmil](/molmil-images/mine/3v4p) | crystal structure of a4b7 headpiece complexed with Fab ACT-1 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Yu, Y, Zhu, J, Springer, T.A. | Deposit date: | 2011-12-15 | Release date: | 2012-01-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Structural specializations of a4b7, an Integrin that Mediates Rolling Adhesion J.Cell Biol., 196, 2012
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2X7R
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![BU of 2x7r by Molmil](/molmil-images/mine/2x7r) | |
3FB8
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![BU of 3fb8 by Molmil](/molmil-images/mine/3fb8) | KcsA Potassium channel in the open-conductive state with 20 A opening at T112 in the presence of Rb+ ion | Descriptor: | RUBIDIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ... | Authors: | Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E. | Deposit date: | 2008-11-18 | Release date: | 2010-05-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | KcsA Potassium channel in the open-conductive state
with 20 A opening at T112 in the presence of Rb+ ion TO BE PUBLISHED
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