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6PCX	Crystal Structure of a H5N1 influenza virus hemagglutinin at pH 6.0 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Hemagglutinin, ... Authors: Antanasijevic, A, Durst, M.A, Lavie, A, Caffrey, M. Deposit date: 2019-06-18 Release date: 2019-11-13 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.11 Å) Cite: Identification of a pH sensor in Influenza hemagglutinin using X-ray crystallography. J.Struct.Biol., 209, 2020
7QA4	Crystal structure of stabilized H3N2 A/Hong Kong/1/1968 Hemagglutinin at 2.2 Angstrom Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Milder, F.J, Langedijk, J.P.M. Deposit date: 2021-11-16 Release date: 2022-02-02 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.19 Å) Cite: Universal stabilization of the influenza hemagglutinin by structure-based redesign of the pH switch regions. Proc.Natl.Acad.Sci.USA, 119, 2022
7RCR	Crystal Structure of the refolded Hemagglutinin head domain of Influenza A virus A/Ohio/09/2015 Descriptor: 1,2-ETHANEDIOL, Hemagglutinin Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2021-07-08 Release date: 2021-08-04 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal Structure of the refolded Hemagglutinin head domain of Influenzavirus A Influenza A virus A/Ohio/09/2015 to be published
7MFG	Cryo-EM structure of the VRC310 clinical trial, vaccine-elicited, human antibody 310-030-1D06 Fab in complex with an H1 NC99 HA trimer Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 310-030-1D06 Heavy, 310-030-1D06 Light, ... Authors: Gorman, J, Kwong, P.D. Deposit date: 2021-04-09 Release date: 2021-11-03 Last modified: 2024-10-09 Method: ELECTRON MICROSCOPY (3.87 Å) Cite: A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination. Nat Med, 28, 2022
7MEM	CryoEM structure of monoclonal Fab 045-09 2B05 binding the lateral patch of influenza virus H1 HA Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of monoclonal antibody 045-09 2B05, ... Authors: Han, J, Ward, A. Deposit date: 2021-04-06 Release date: 2021-07-28 Last modified: 2024-11-20 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: First exposure to the pandemic H1N1 virus induced broadly neutralizing antibodies targeting hemagglutinin head epitopes. Sci Transl Med, 13, 2021
7RDH	Crystal structure of the de novo designed binding protein H3mb in complex with the 1968 influenza A virus hemagglutinin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, De novo designed protein H3mb, ... Authors: Kadam, R.U, Wilson, I.A. Deposit date: 2021-07-09 Release date: 2022-05-04 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Design of protein-binding proteins from the target structure alone. Nature, 605, 2022
7YHK	Cryo-EM structure of the HA trimer of A/Beijing/262/1995(H1N1) in complex with neutralizing antibody 12H5 Descriptor: 12H5 heavy chain, 12H5 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Zheng, Q, Li, S, Li, T, Xue, W, Sun, H. Deposit date: 2022-07-13 Release date: 2022-08-17 Last modified: 2024-11-13 Method: ELECTRON MICROSCOPY (3.14 Å) Cite: Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses. Nat Commun, 13, 2022
8DIM	CryoEM structure of Influenza A virus A/Ohio/09/2015 hemagglutinin bound to CR6261 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CR6261 Fab heavy chain, CR6261 Fab light chain, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2022-06-29 Release date: 2022-11-16 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (2.62 Å) Cite: CryoEM structure of Influenza A virus A/Ohio/09/2015 hemagglutinin bound to CR6261 Fab To Be Published
6CHX	High Resolution Crystal Structure of the Hemagglutinin H1 Head Domain of Influenza A virus Solomon Islands Descriptor: Hemagglutinin Authors: Dong, J, Sevy, A.M, Crowe, J.E. Deposit date: 2018-02-23 Release date: 2019-02-27 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.4 Å) Cite: High Resolution Crystal Structure of the Hemagglutinin H1 Head Domain of Influenza A virus Solomon Islands To Be Published
6CF5	Crystal structure of the A/Viet Nam/1203/2004(H5N1) influenza virus hemagglutinin in complex with small molecule N-Cyclohexyltaurine Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Wilson, I.A, Kadam, R.U. Deposit date: 2018-02-13 Release date: 2018-04-04 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.04 Å) Cite: A small-molecule fragment that emulates binding of receptor and broadly neutralizing antibodies to influenza A hemagglutinin. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8DIU	Cryo-EM structure of influenza A virus A/Bayern/7/1995 hemagglutinin bound to CR6261 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR6261 Fab heavy chain, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2022-06-29 Release date: 2022-12-14 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (2.61 Å) Cite: CryoEM structure of influenza A virus A/Bayern/7/1995 hemagglutinin bound to CR6261 Fab To be published
6CFG	Crystal structure of the A/Vietnam/1203/2004 (H5N1) influenza virus hemagglutinin in complex with small molecule JNJ4796 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... Authors: Kadam, R.U, Wilson, I.A. Deposit date: 2018-02-14 Release date: 2019-02-13 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.32 Å) Cite: A small-molecule fusion inhibitor of influenza virus is orally active in mice. Science, 363, 2019
6V48	The crystal structure of hemagglutinin from A/mallard/Gurjev/263/1982 (H14N5) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... Authors: Yang, H, Stevens, J. Deposit date: 2019-11-27 Release date: 2020-06-17 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3.004 Å) Cite: Molecular characterization and three-dimensional structures of avian H8, H11, H14, H15 and swine H4 influenza virus hemagglutinins Heliyon, 6, 2020
7DEA	Structure of an avian influenza H5 hemagglutinin from the influenza virus A/duck Northern China/22/2017 (H5N6) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin Authors: Sun, H, Sun, H, Song, J, Zhang, W, Wei, X, Qi, J, Gao, G.F, Liu, J. Deposit date: 2020-11-03 Release date: 2021-11-03 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.84 Å) Cite: Haemagglutinin and neuraminidase acid stability in H5N6 avian influenza virus confers infection adaptation in mammals To Be Published
7DEB	Structure of an avian influenza H5 hemagglutinin from the influenza virus A/duck/Eastern China/L0230/2010 (H5N2) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Sun, H, Sun, H, Song, J, Zhang, W, Qi, J, Gao, G.F, Liu, J. Deposit date: 2020-11-03 Release date: 2021-11-03 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Haemagglutinin and neuraminidase acid stability in H5N6 avian influenza virus confers infection adaptation in mammals To Be Published
6V46	The crystal structure of hemagglutinin from A/turkey/Ontario/6118/1968 (H8N4) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Yang, H, Stevens, J. Deposit date: 2019-11-27 Release date: 2020-06-17 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.248 Å) Cite: Molecular characterization and three-dimensional structures of avian H8, H11, H14, H15 and swine H4 influenza virus hemagglutinins Heliyon, 6, 2020
7DKJ	Hemagglutinin Influenza A virus (A/Okuda/1957(H2N2) bound with a neutralizing antibody Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fv-clasp heavy chain, Fv-clasp light chain, ... Authors: Shirouzu, M. Deposit date: 2020-11-24 Release date: 2021-11-24 Last modified: 2024-11-20 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Hemagglutinin Influenza A virus (A/Okuda/1957(H2N2) bound with a neutralizing antibody To Be Published
6V49	The crystal structure of hemagglutinin from A/wedge-tailed shearwater/Western Australia/2576/1979 (H15N9) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... Authors: Yang, H, Stevens, J. Deposit date: 2019-11-27 Release date: 2020-06-17 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Molecular characterization and three-dimensional structures of avian H8, H11, H14, H15 and swine H4 influenza virus hemagglutinins Heliyon, 6, 2020
6D0U	Crystal structure of C05 V110P/A117E mutant bound to H3 influenza hemagglutinin, HA1 subunit Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody C05 V110P/A117E mutant, heavy chain, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2018-04-11 Release date: 2019-01-16 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (3.25 Å) Cite: Multistate design of influenza antibodies improves affinity and breadth against seasonal viruses. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
8DIS	CryoEM structure of Influenza A virus A/Melbourne/1/1946 (H1N1) hemagglutinin bound to CR6261 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR6261 Fab heavy chain, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2022-06-29 Release date: 2023-06-07 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (2.62 Å) Cite: CryoEM structure of Influenza A virus A/Melbourne/1/1946 (H1N1) hemagglutinin bound to CR6261 Fab To be published
6VMZ	Crystal Structure of a H5N1 influenza virus hemagglutinin with CBS1117 Descriptor: 2,6-dichloro-N-[1-(propan-2-yl)piperidin-4-yl]benzamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin Authors: Antanasijevic, A, Durst, M.A, Lavie, A, Caffrey, M. Deposit date: 2020-01-28 Release date: 2020-07-01 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure of avian influenza hemagglutinin in complex with a small molecule entry inhibitor. Life Sci Alliance, 3, 2020
3EYM	Structure of Influenza Haemagglutinin in complex with an inhibitor of membrane fusion Descriptor: 2-tert-butylbenzene-1,4-diol, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain Authors: Russell, R.J, Kerry, P.S, Stevens, D.A, Steinhauer, D.A, Martin, S.R, Gamblin, S.J, Skehel, J.J. Deposit date: 2008-10-21 Release date: 2009-01-13 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion Proc.Natl.Acad.Sci.USA, 105, 2008
3EYJ	Structure of Influenza Haemagglutinin in complex with an inhibitor of membrane fusion Descriptor: Hemagglutinin HA1 chain, Hemagglutinin HA2 chain Authors: Russell, R.J, Kerry, P.S, Stevens, D.J, Steinahuer, D.A, Martin, S.R, Gamblin, S.J, Skehel, J.J. Deposit date: 2008-10-21 Release date: 2009-01-13 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion Proc.Natl.Acad.Sci.USA, 105, 2008
3EYK	Structure of Influenza Haemagglutinin in complex with an inhibitor of membrane fusion Descriptor: 2-tert-butylbenzene-1,4-diol, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain Authors: Russell, R.J, Kerry, P.S, Stevens, D.J, Steinhauer, D.A, Martin, S.R, Gamblin, S.J, Skehel, J.J. Deposit date: 2008-10-21 Release date: 2009-01-13 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion Proc.Natl.Acad.Sci.USA, 105, 2008
3FKU	Crystal structure of influenza hemagglutinin (H5) in complex with a broadly neutralizing antibody F10 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, Hemagglutinin HA2 chain, ... Authors: Hwang, W.C, Santelli, E, Stec, B, Wei, G, Cadwell, G, Bankston, L.A, Sui, J, Perez, S, Aird, D, Chen, L.M, Ali, M, Murakami, A, Yammanuru, A, Han, T, Cox, N, Donis, R.O, Liddington, R.C, Marasco, W.A. Deposit date: 2008-12-17 Release date: 2009-02-24 Last modified: 2024-12-25 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses. Nat.Struct.Mol.Biol., 16, 2009

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