7MEM

CryoEM structure of monoclonal Fab 045-09 2B05 binding the lateral patch of influenza virus H1 HA

Summary for 7MEM

• Entry DOI: 10.2210/pdb7mem/pdb
• EMDB information: 23792 23793 23794 23795 23796 23797 23798
• Descriptor: Hemagglutinin HA1 chain, Light chain of monoclonal antibody 045-09 2B05, Heavy chain of monoclonal antibody 045-09 2B05, ... (7 entities in total)
• Functional Keywords: hemagglutinin, monoclonal antibody, influenza virus, immune system, viral protein-immune system complex, viral protein/immune system
• Biological source: Influenza A virus (strain swl A/California/04/2009 H1N1); More
• Total number of polymer chains: 12
• Total formula weight: 247328.77

Authors

Han, J.,Ward, A. (deposition date: 2021-04-06, release date: 2021-07-28)

• Primary citation: Guthmiller, J.J.,Han, J.,Li, L.,Freyn, A.W.,Liu, S.T.H.,Stovicek, O.,Stamper, C.T.,Dugan, H.L.,Tepora, M.E.,Utset, H.A.,Bitar, D.J.,Hamel, N.J.,Changrob, S.,Zheng, N.Y.,Huang, M.,Krammer, F.,Nachbagauer, R.,Palese, P.,Ward, A.B.,Wilson, P.C.; First exposure to the pandemic H1N1 virus induced broadly neutralizing antibodies targeting hemagglutinin head epitopes.; Sci Transl Med, 13:-, 2021; PubMed: 34078743; DOI: 10.1126/scitranslmed.abg4535

Experimental method

ELECTRON MICROSCOPY (3.2 Å)